GO Annotations Graph

• Symbol: Ccnb1
• Name: cyclin B1
• ID: MGI:88302

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	ISO	J:164563
Molecular Function	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	IBA	J:265628
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0005113	patched binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:81361
Molecular Function	GO:0005515	protein binding	IPI	J:81361
Molecular Function	GO:0005515	protein binding	IPI	J:78410
Molecular Function	GO:0005515	protein binding	IPI	J:78410
Molecular Function	GO:0005515	protein binding	IPI	J:78410
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0044389	ubiquitin-like protein ligase binding	ISO	J:164563
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0097125	cyclin B1-CDK1 complex	ISO	J:164563
Cellular Component	GO:0097125	cyclin B1-CDK1 complex	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:121535
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:47430
Cellular Component	GO:0005759	mitochondrial matrix	ISO	J:164563
Cellular Component	GO:0005759	mitochondrial matrix	IDA	J:240380
Cellular Component	GO:0005759	mitochondrial matrix	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:148330
Cellular Component	GO:0005634	nucleus	IDA	J:106653
Cellular Component	GO:0005634	nucleus	ISO	J:101015
Cellular Component	GO:0005634	nucleus	IDA	J:89060
Cellular Component	GO:0005634	nucleus	IDA	J:121535
Cellular Component	GO:0000940	outer kinetochore	ISO	J:164563
Cellular Component	GO:0000922	spindle pole	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0001701	in utero embryonic development	IMP	J:47430
Biological Process	GO:0044772	mitotic cell cycle phase transition	IBA	J:265628
Biological Process	GO:0007080	mitotic metaphase plate congression	ISO	J:164563
Biological Process	GO:0007080	mitotic metaphase plate congression	IBA	J:265628
Biological Process	GO:0007052	mitotic spindle organization	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:155856
Biological Process	GO:0001933	negative regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:0001556	oocyte maturation	ISO	J:155856
Biological Process	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore	ISO	J:164563
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	ISO	J:155856
Biological Process	GO:0045787	positive regulation of cell cycle	IDA	J:197739
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	IMP	J:197739
Biological Process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:1905448	positive regulation of mitochondrial ATP synthesis coupled electron transport	ISO	J:164563
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0031442	positive regulation of mRNA 3'-end processing	ISO	J:155856
Biological Process	GO:0045860	positive regulation of protein kinase activity	ISO	J:155856
Biological Process	GO:0006468	protein phosphorylation	IDA	J:78410
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:155856
Biological Process	GO:0060623	regulation of chromosome condensation	ISO	J:155856
Biological Process	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	IBA	J:265628
Biological Process	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint	ISO	J:164563