GO Annotations Graph

• Symbol: Cbr1
• Name: carbonyl reductase 1
• ID: MGI:88284

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0047021	15-hydroxyprostaglandin dehydrogenase (NADP+) activity	IEA	J:72245
Molecular Function	GO:0047020	15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity	IEA	J:72245
Molecular Function	GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	IEA	J:72245
Molecular Function	GO:0004090	carbonyl reductase (NADPH) activity	ISO	J:155856
Molecular Function	GO:0004090	carbonyl reductase (NADPH) activity	ISO	J:164563
Molecular Function	GO:0004090	carbonyl reductase (NADPH) activity	IBA	J:265628
Molecular Function	GO:0004090	carbonyl reductase (NADPH) activity	TAS	J:33127
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Molecular Function	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	ISO	J:164563
Molecular Function	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IDA	J:256366
Molecular Function	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	ISO	J:164563
Molecular Function	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IDA	J:256366
Molecular Function	GO:0050221	prostaglandin-E2 9-reductase activity	IEA	J:72245
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0005902	microvillus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0035003	subapical complex	IDA	J:114927
Biological Process	GO:0008211	glucocorticoid metabolic process	ISO	J:164563
Biological Process	GO:0008211	glucocorticoid metabolic process	IDA	J:256366
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process	ISO	J:164563
Biological Process	GO:0042373	vitamin K metabolic process	ISO	J:164563
Biological Process	GO:0006805	xenobiotic metabolic process	ISO	J:164563