GO Annotations Graph

• Symbol: Atp6v0c
• Name: ATPase, H+ transporting, lysosomal V0 subunit C
• ID: MGI:88116

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008553	P-type proton-exporting transporter activity	ISA	J:71376
Molecular Function	GO:0005515	protein binding	IPI	J:79288
Molecular Function	GO:0005515	protein binding	IPI	J:79288
Molecular Function	GO:0015078	proton transmembrane transporter activity	IEA	J:72247
Molecular Function	GO:0046961	proton-transporting ATPase activity, rotational mechanism	IEA	J:72247
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0005764	lysosome	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain	IEA	J:72247
Cellular Component	GO:0033176	proton-transporting V-type ATPase complex	IDA	J:327410
Cellular Component	GO:0033179	proton-transporting V-type ATPase, V0 domain	TAS	J:71376
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:1902495	transmembrane transporter complex	IDA	J:327410
Cellular Component	GO:0016471	vacuolar proton-transporting V-type ATPase complex	TAS	J:71376
Biological Process	GO:0007042	lysosomal lumen acidification	TAS	J:71376
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:1904093	negative regulation of autophagic cell death	ISO	J:155856
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	ISO	J:164563
Biological Process	GO:1902600	proton transmembrane transport	ISA	J:71376
Biological Process	GO:0007035	vacuolar acidification	TAS	J:71376