GO Annotations Graph

• Symbol: Agtr2
• Name: angiotensin II receptor, type 2
• ID: MGI:87966

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004945	angiotensin type II receptor activity	ISO	J:155856
Molecular Function	GO:0004945	angiotensin type II receptor activity	ISO	J:164563
Molecular Function	GO:0004945	angiotensin type II receptor activity	IBA	J:265628
Molecular Function	GO:0004945	angiotensin type II receptor activity	IDA	J:51954
Molecular Function	GO:0004945	angiotensin type II receptor activity	IPI	J:51954
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Biological Process	GO:0035932	aldosterone secretion	ISO	J:155856
Biological Process	GO:0002033	angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure	IMP	J:56635
Biological Process	GO:0097746	blood vessel diameter maintenance	IEA	J:72247
Biological Process	GO:0002035	brain renin-angiotensin system	IDA	J:51954
Biological Process	GO:0061049	cell growth involved in cardiac muscle cell development	ISO	J:155856
Biological Process	GO:0007166	cell surface receptor signaling pathway	ISO	J:164563
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	ISO	J:155856
Biological Process	GO:0021695	cerebellar cortex development	ISO	J:155856
Biological Process	GO:0042416	dopamine biosynthetic process	ISO	J:155856
Biological Process	GO:0035640	exploration behavior	IMP	J:29457
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007199	G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger	IDA	J:154830
Biological Process	GO:0006954	inflammatory response	ISO	J:155856
Biological Process	GO:0006954	inflammatory response	IBA	J:265628
Biological Process	GO:0006954	inflammatory response	IGI	J:148250
Biological Process	GO:0006954	inflammatory response	IGI	J:148250
Biological Process	GO:0035556	intracellular signal transduction	IDA	J:154830
Biological Process	GO:0006883	intracellular sodium ion homeostasis	ISO	J:155856
Biological Process	GO:0060993	kidney morphogenesis	ISO	J:155856
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	ISO	J:155856
Biological Process	GO:0010459	negative regulation of heart rate	IMP	J:109161
Biological Process	GO:0032304	negative regulation of icosanoid secretion	ISO	J:155856
Biological Process	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway	ISO	J:164563
Biological Process	GO:0010700	negative regulation of norepinephrine secretion	ISO	J:155856
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:78697
Biological Process	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	IMP	J:139561
Biological Process	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0001819	positive regulation of cytokine production	ISO	J:155856
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:139561
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:172881
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0072300	positive regulation of metanephric glomerulus development	IMP	J:139561
Biological Process	GO:0051000	positive regulation of nitric-oxide synthase activity	IDA	J:154830
Biological Process	GO:0032516	positive regulation of phosphoprotein phosphatase activity	ISO	J:164563
Biological Process	GO:0035815	positive regulation of renal sodium excretion	ISO	J:155856
Biological Process	GO:0042981	regulation of apoptotic process	IEA	J:72247
Biological Process	GO:0035566	regulation of metanephros size	IMP	J:139561
Biological Process	GO:0042306	regulation of protein import into nucleus	ISO	J:155856
Biological Process	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	IMP	J:29457
Biological Process	GO:0002018	renin-angiotensin regulation of aldosterone production	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0042311	vasodilation	ISO	J:164563
Biological Process	GO:0042311	vasodilation	ISO	J:155856