GO Annotations Graph

• Symbol: Sorbs3
• Name: sorbin and SH3 domain containing 3
• ID: MGI:700013

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008134	transcription factor binding	IPI	J:98785
Molecular Function	GO:0017166	vinculin binding	ISO	J:164563
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:56246
Cellular Component	GO:0005737	cytoplasm	IDA	J:102860
Cellular Component	GO:0005737	cytoplasm	IDA	J:102860
Cellular Component	GO:0005737	cytoplasm	IDA	J:98785
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0005925	focal adhesion	IDA	J:56246
Cellular Component	GO:0005634	nucleus	IDA	J:56246
Cellular Component	GO:0005634	nucleus	IDA	J:98785
Biological Process	GO:0007015	actin filament organization	IEA	J:72247
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007155	cell adhesion	IEA	J:72247
Biological Process	GO:0031589	cell-substrate adhesion	IDA	J:56246
Biological Process	GO:0000165	MAPK cascade	IMP	J:102860
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:98785
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:98785
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:98785
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:98785
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:98785
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:98785
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:98785
Biological Process	GO:0043410	positive regulation of MAPK cascade	IMP	J:102860
Biological Process	GO:0051496	positive regulation of stress fiber assembly	ISO	J:164563