GO Annotations Graph

• Symbol: Chrna10
• Name: cholinergic receptor, nicotinic, alpha polypeptide 10
• ID: MGI:3609260

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	IBA	J:265628
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	IMP	J:130585
Molecular Function	GO:0005515	protein binding	IPI	J:116349
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	ISO	J:155856
Cellular Component	GO:0005892	acetylcholine-gated channel complex	NAS	J:130585
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0098981	cholinergic synapse	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0099634	postsynaptic specialization membrane	ISO	J:155856
Cellular Component	GO:0045202	synapse	IMP	J:130585
Cellular Component	GO:0045202	synapse	IBA	J:265628
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	IMP	J:130585
Biological Process	GO:0042472	inner ear morphogenesis	IMP	J:130585
Biological Process	GO:0051899	membrane depolarization	ISO	J:155856
Biological Process	GO:0051899	membrane depolarization	ISO	J:164563
Biological Process	GO:0051899	membrane depolarization	IMP	J:130585
Biological Process	GO:0034220	monoatomic ion transmembrane transport	IBA	J:265628
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0050877	nervous system process	IBA	J:265628
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:73065
Biological Process	GO:0042391	regulation of membrane potential	IBA	J:265628
Biological Process	GO:0010996	response to auditory stimulus	ISO	J:155856
Biological Process	GO:0010996	response to auditory stimulus	IMP	J:144698
Biological Process	GO:0007165	signal transduction	IBA	J:265628
Biological Process	GO:0007271	synaptic transmission, cholinergic	IMP	J:130585