GO Annotations Graph

• Symbol: Arhgef15
• Name: Rho guanine nucleotide exchange factor 15
• ID: MGI:3045246

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005096	GTPase activator activity	IEA	J:60000
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:155856
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IDA	J:167914
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:167914
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0030425	dendrite	IDA	J:167914
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:326507
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:326507
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:326507
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:326507
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:326507
Cellular Component	GO:0098794	postsynapse	IDA	J:326507
Cellular Component	GO:0098794	postsynapse	IMP	J:326507
Biological Process	GO:0090630	activation of GTPase activity	IBA	J:265628
Biological Process	GO:2000297	negative regulation of synapse maturation	IMP	J:167914
Biological Process	GO:0051496	positive regulation of stress fiber assembly	ISO	J:155856
Biological Process	GO:0050790	regulation of catalytic activity	ISO	J:164563
Biological Process	GO:0050790	regulation of catalytic activity	ISO	J:155856
Biological Process	GO:0150052	regulation of postsynapse assembly	IMP	J:326507
Biological Process	GO:0150052	regulation of postsynapse assembly	IDA	J:326507
Biological Process	GO:0150052	regulation of postsynapse assembly	IMP	J:326507
Biological Process	GO:0061299	retina vasculature morphogenesis in camera-type eye	IMP	J:188649