GO Annotations Graph

• Symbol: Il17f
• Name: interleukin 17F
• ID: MGI:2676631

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	ISO	J:164563
Molecular Function	GO:0019955	cytokine binding	ISO	J:164563
Molecular Function	GO:0005126	cytokine receptor binding	IPI	J:153022
Molecular Function	GO:0005515	protein binding	IPI	J:155093
Molecular Function	GO:0046982	protein heterodimerization activity	IDA	J:155093
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:155093
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005615	extracellular space	IDA	J:155093
Cellular Component	GO:0005615	extracellular space	IDA	J:153850
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0051216	cartilage development	ISO	J:164563
Biological Process	GO:0050829	defense response to Gram-negative bacterium	IMP	J:143719
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IMP	J:143719
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0006954	inflammatory response	IEA	J:60000
Biological Process	GO:0006954	inflammatory response	IEA	J:72247
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0016525	negative regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0002225	positive regulation of antimicrobial peptide production	IDA	J:143719
Biological Process	GO:2000340	positive regulation of chemokine (C-X-C motif) ligand 1 production	ISO	J:164563
Biological Process	GO:0001819	positive regulation of cytokine production	ISO	J:164563
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	IDA	J:153850
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	IDA	J:134412
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	IGI	J:134412
Biological Process	GO:0032755	positive regulation of interleukin-6 production	IMP	J:161934
Biological Process	GO:0032755	positive regulation of interleukin-6 production	ISO	J:164563
Biological Process	GO:0032761	positive regulation of lymphotoxin A production	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:124638
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:124638
Biological Process	GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	ISO	J:164563
Biological Process	GO:0032663	regulation of interleukin-2 production	ISO	J:164563
Biological Process	GO:0032675	regulation of interleukin-6 production	ISO	J:164563
Biological Process	GO:0032677	regulation of interleukin-8 production	ISO	J:164563
Biological Process	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	ISO	J:164563