GO Annotations Graph

• Symbol: Eif2b5
• Name: eukaryotic translation initiation factor 2B, subunit 5 epsilon
• ID: MGI:2446176

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:164563
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:155856
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:164563
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:155856
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IBA	J:265628
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:73065
Molecular Function	GO:0003743	translation initiation factor activity	ISO	J:164563
Molecular Function	GO:0003743	translation initiation factor activity	IBA	J:265628
Molecular Function	GO:0031369	translation initiation factor binding	ISO	J:155856
Molecular Function	GO:0031369	translation initiation factor binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:82058
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	ISO	J:164563
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	ISO	J:155856
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	IBA	J:265628
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	ISO	J:73065
Cellular Component	GO:0005634	nucleus	IDA	J:82058
Biological Process	GO:0007568	aging	ISO	J:155856
Biological Process	GO:0014002	astrocyte development	ISO	J:164563
Biological Process	GO:0048708	astrocyte differentiation	ISO	J:164563
Biological Process	GO:0042552	myelination	ISO	J:164563
Biological Process	GO:0014003	oligodendrocyte development	ISO	J:164563
Biological Process	GO:0001541	ovarian follicle development	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0045727	positive regulation of translation	ISO	J:155856
Biological Process	GO:0034976	response to endoplasmic reticulum stress	ISO	J:164563
Biological Process	GO:0009749	response to glucose	ISO	J:155856
Biological Process	GO:0009408	response to heat	ISO	J:164563
Biological Process	GO:0009408	response to heat	ISO	J:155856
Biological Process	GO:0043434	response to peptide hormone	ISO	J:155856
Biological Process	GO:0050852	T cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0006412	translation	IEA	J:60000
Biological Process	GO:0006413	translational initiation	ISO	J:164563