GO Annotations Graph

• Symbol: Fa2h
• Name: fatty acid 2-hydroxylase
• ID: MGI:2443327

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0080132	fatty acid alpha-hydroxylase activity	ISO	J:155856
Molecular Function	GO:0080132	fatty acid alpha-hydroxylase activity	ISO	J:164563
Molecular Function	GO:0080132	fatty acid alpha-hydroxylase activity	IBA	J:265628
Molecular Function	GO:0080132	fatty acid alpha-hydroxylase activity	IDA	J:117530
Molecular Function	GO:0080132	fatty acid alpha-hydroxylase activity	IDA	J:117271
Molecular Function	GO:0020037	heme binding	IEA	J:72247
Molecular Function	GO:0005506	iron ion binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:72247
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:117530
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IEA	J:60000
Cellular Component	GO:0016020	membrane	ISO	J:164563
Biological Process	GO:0032286	central nervous system myelin maintenance	IMP	J:171655
Biological Process	GO:0032286	central nervous system myelin maintenance	IMP	J:143373
Biological Process	GO:0032286	central nervous system myelin maintenance	IMP	J:171655
Biological Process	GO:0046513	ceramide biosynthetic process	IMP	J:266470
Biological Process	GO:0046513	ceramide biosynthetic process	ISO	J:164563
Biological Process	GO:0061436	establishment of skin barrier	ISO	J:164563
Biological Process	GO:0006633	fatty acid biosynthetic process	IEA	J:60000
Biological Process	GO:0006631	fatty acid metabolic process	IBA	J:265628
Biological Process	GO:0006631	fatty acid metabolic process	IDA	J:117271
Biological Process	GO:0006682	galactosylceramide biosynthetic process	IDA	J:117530
Biological Process	GO:0006682	galactosylceramide biosynthetic process	IMP	J:143373
Biological Process	GO:0006682	galactosylceramide biosynthetic process	ISO	J:155856
Biological Process	GO:0006679	glucosylceramide biosynthetic process	IMP	J:175386
Biological Process	GO:0008610	lipid biosynthetic process	IEA	J:72247
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:72247
Biological Process	GO:0030258	lipid modification	IDA	J:117530
Biological Process	GO:0030258	lipid modification	IMP	J:143373
Biological Process	GO:0032287	peripheral nervous system myelin maintenance	IMP	J:143373
Biological Process	GO:0044857	plasma membrane raft organization	IMP	J:266470
Biological Process	GO:1904697	regulation of acinar cell proliferation	IMP	J:175386
Biological Process	GO:0042634	regulation of hair cycle	IMP	J:175386
Biological Process	GO:1904002	regulation of sebum secreting cell proliferation	IMP	J:175386
Biological Process	GO:0001949	sebaceous gland cell differentiation	IMP	J:175386
Biological Process	GO:0006665	sphingolipid metabolic process	IEA	J:60000