GO Annotations Graph

• Symbol: Bbc3
• Name: BCL2 binding component 3
• ID: MGI:2181667

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051117	ATPase binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:247400
Molecular Function	GO:0005515	protein binding	IPI	J:101198
Molecular Function	GO:0005515	protein binding	IPI	J:168877
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0005740	mitochondrial envelope	ISO	J:76185
Cellular Component	GO:0005739	mitochondrion	ISS	J:76185
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0097143	PUMA-BCL-xl complex	ISO	J:164563
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ISS	J:76185
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	ISO	J:164563
Biological Process	GO:0097190	apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0097190	apoptotic signaling pathway	ISO	J:77072
Biological Process	GO:0071479	cellular response to ionizing radiation	IGI	J:115191
Biological Process	GO:0071479	cellular response to ionizing radiation	IGI	J:115191
Biological Process	GO:0008340	determination of adult lifespan	IGI	J:170216
Biological Process	GO:0006974	DNA damage response	IGI	J:170216
Biological Process	GO:0097194	execution phase of apoptosis	ISO	J:164563
Biological Process	GO:0097194	execution phase of apoptosis	ISS	J:76185
Biological Process	GO:0097194	execution phase of apoptosis	IBA	J:265628
Biological Process	GO:0044346	fibroblast apoptotic process	IMP	J:86466
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	IEA	J:72247
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	ISO	J:76185
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IMP	J:101198
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IMP	J:190239
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IMP	J:219625
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IMP	J:167725
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	ISO	J:164563
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	IBA	J:265628
Biological Process	GO:0070227	lymphocyte apoptotic process	IMP	J:86466
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:76185
Biological Process	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration	ISO	J:164563
Biological Process	GO:0045926	negative regulation of growth	ISS	J:76185
Biological Process	GO:0045926	negative regulation of growth	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	IEA	J:72247
Biological Process	GO:2001056	positive regulation of cysteine-type endopeptidase activity	IMP	J:167725
Biological Process	GO:2001056	positive regulation of cysteine-type endopeptidase activity	IMP	J:190239
Biological Process	GO:2000271	positive regulation of fibroblast apoptotic process	IMP	J:86466
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	ISO	J:155856
Biological Process	GO:0070230	positive regulation of lymphocyte apoptotic process	IMP	J:86466
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IMP	J:190239
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	IMP	J:167725
Biological Process	GO:0032464	positive regulation of protein homooligomerization	ISO	J:164563
Biological Process	GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	IBA	J:265628
Biological Process	GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	IMP	J:138066
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	ISO	J:164563
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	IBA	J:265628
Biological Process	GO:0070234	positive regulation of T cell apoptotic process	IMP	J:111822
Biological Process	GO:0070245	positive regulation of thymocyte apoptotic process	IGI	J:170216
Biological Process	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	IMP	J:138066
Biological Process	GO:0001836	release of cytochrome c from mitochondria	ISS	J:76185
Biological Process	GO:0001836	release of cytochrome c from mitochondria	ISO	J:164563
Biological Process	GO:0001836	release of cytochrome c from mitochondria	IBA	J:265628
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	ISO	J:164563
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IDA	J:167725
Biological Process	GO:0034976	response to endoplasmic reticulum stress	ISO	J:164563
Biological Process	GO:0070231	T cell apoptotic process	IMP	J:111822
Biological Process	GO:1901998	toxin transport	IMP	J:197389