Kcnn2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Kcnn2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
MGI:2153182

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051393	alpha-actinin binding	ISO	J:164563
Molecular Function	GO:0015269	calcium-activated potassium channel activity	ISO	J:164563
Molecular Function	GO:0005516	calmodulin binding	ISO	J:155856
Molecular Function	GO:0005516	calmodulin binding	IBA	J:265628
Molecular Function	GO:0005242	inward rectifier potassium channel activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:231015
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0016286	small conductance calcium-activated potassium channel activity	IMP	J:153742
Molecular Function	GO:0016286	small conductance calcium-activated potassium channel activity	ISO	J:155856
Molecular Function	GO:0016286	small conductance calcium-activated potassium channel activity	IMP	J:176552
Molecular Function	GO:0016286	small conductance calcium-activated potassium channel activity	ISO	J:164563
Molecular Function	GO:0016286	small conductance calcium-activated potassium channel activity	IBA	J:265628
Molecular Function	GO:0016286	small conductance calcium-activated potassium channel activity	ISO	J:72099
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	IBA	J:265628
Cellular Component	GO:0043197	dendritic spine	IDA	J:122513
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:326648
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:326648
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:224839
Cellular Component	GO:0098978	glutamatergic synapse	EXP	J:224839
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9663768
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:122513
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:326648
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:326648
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:326648
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:326648
Cellular Component	GO:0042383	sarcolemma	IDA	J:153742
Cellular Component	GO:0005790	smooth endoplasmic reticulum	IDA	J:122513
Cellular Component	GO:0030315	T-tubule	IDA	J:130245
Cellular Component	GO:0030018	Z disc	IDA	J:153742
Cellular Component	GO:0030018	Z disc	IDA	J:130245
Cellular Component	GO:0030018	Z disc	IDA	J:212181
Biological Process	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential	IMP	J:176552
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:224839
Biological Process	GO:0050804	modulation of chemical synaptic transmission	EXP	J:224839
Biological Process	GO:0043268	positive regulation of potassium ion transport	ISO	J:155856
Biological Process	GO:0071805	potassium ion transmembrane transport	IMP	J:176552
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0071805	potassium ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006813	potassium ion transport	ISO	J:155856
Biological Process	GO:0048168	regulation of neuronal synaptic plasticity	ISO	J:155856
Biological Process	GO:1901379	regulation of potassium ion transmembrane transport	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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