GO Annotations Graph

• Symbol: Ces1d
• Name: carboxylesterase 1D
• ID: MGI:2148202

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0106435	carboxylesterase activity	ISO	J:164563
Molecular Function	GO:0106435	carboxylesterase activity	IMP	J:158743
Molecular Function	GO:0106435	carboxylesterase activity	IMP	J:158743
Molecular Function	GO:0052689	carboxylic ester hydrolase activity	IDA	J:183224
Molecular Function	GO:0052689	carboxylic ester hydrolase activity	IBA	J:265628
Molecular Function	GO:0030339	fatty-acyl-ethyl-ester synthase activity	IEA	J:72245
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0050253	retinyl-palmitate esterase activity	ISO	J:155856
Molecular Function	GO:0004771	sterol esterase activity	ISO	J:164563
Molecular Function	GO:0004771	sterol esterase activity	IDA	J:183224
Molecular Function	GO:0004806	triglyceride lipase activity	IDA	J:183224
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:183224
Cellular Component	GO:0005829	cytosol	IMP	J:276211
Cellular Component	GO:0005829	cytosol	IDA	J:111854
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:276211
Cellular Component	GO:0005788	endoplasmic reticulum lumen	IDA	J:183224
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0005811	lipid droplet	IDA	J:183224
Cellular Component	GO:0005811	lipid droplet	ISO	J:164563
Cellular Component	GO:0005811	lipid droplet	IBA	J:265628
Cellular Component	GO:0005811	lipid droplet	IDA	J:276211
Cellular Component	GO:0005811	lipid droplet	IDA	J:111854
Biological Process	GO:0006637	acyl-CoA metabolic process	TAS	J:113779
Biological Process	GO:0046464	acylglycerol catabolic process	IDA	J:183224
Biological Process	GO:0071397	cellular response to cholesterol	ISO	J:164563
Biological Process	GO:0070417	cellular response to cold	IMP	J:276211
Biological Process	GO:0071404	cellular response to low-density lipoprotein particle stimulus	ISO	J:164563
Biological Process	GO:0006695	cholesterol biosynthetic process	ISO	J:164563
Biological Process	GO:0042632	cholesterol homeostasis	ISO	J:164563
Biological Process	GO:0008203	cholesterol metabolic process	ISO	J:164563
Biological Process	GO:0060086	circadian temperature homeostasis	IMP	J:276211
Biological Process	GO:0060086	circadian temperature homeostasis	IMP	J:276211
Biological Process	GO:0106106	cold-induced thermogenesis	IMP	J:276211
Biological Process	GO:0106106	cold-induced thermogenesis	IMP	J:276211
Biological Process	GO:0061725	cytosolic lipolysis	IMP	J:276211
Biological Process	GO:0061725	cytosolic lipolysis	IMP	J:276211
Biological Process	GO:0061725	cytosolic lipolysis	IMP	J:276211
Biological Process	GO:0030855	epithelial cell differentiation	ISO	J:164563
Biological Process	GO:0016042	lipid catabolic process	NAS	J:183224
Biological Process	GO:0016042	lipid catabolic process	IBA	J:265628
Biological Process	GO:0016042	lipid catabolic process	IDA	J:70660
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0051791	medium-chain fatty acid metabolic process	ISO	J:164563
Biological Process	GO:0010887	negative regulation of cholesterol storage	ISO	J:164563
Biological Process	GO:0010875	positive regulation of cholesterol efflux	ISO	J:164563
Biological Process	GO:0090205	positive regulation of cholesterol metabolic process	ISO	J:164563
Biological Process	GO:0061411	positive regulation of transcription from RNA polymerase II promoter in response to cold	IMP	J:276211
Biological Process	GO:0070857	regulation of bile acid biosynthetic process	ISO	J:164563
Biological Process	GO:0120188	regulation of bile acid secretion	ISO	J:164563
Biological Process	GO:0009636	response to toxic substance	TAS	J:113779
Biological Process	GO:0043691	reverse cholesterol transport	ISO	J:164563
Biological Process	GO:0019626	short-chain fatty acid catabolic process	IDA	J:111854
Biological Process	GO:0034379	very-low-density lipoprotein particle assembly	IMP	J:158743