GO Annotations Graph

• Symbol: Usp22
• Name: ubiquitin specific peptidase 22
• ID: MGI:2144157

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	ISO	J:164563
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	ISO	J:164563
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	IDA	J:105884
Molecular Function	GO:0008234	cysteine-type peptidase activity	IEA	J:60000
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0140936	histone H2B deubiquitinase activity	ISO	J:164563
Molecular Function	GO:0010485	histone H4 acetyltransferase activity	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0030374	nuclear receptor coactivator activity	ISO	J:164563
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0000124	SAGA complex	ISO	J:164563
Cellular Component	GO:0000124	SAGA complex	NAS	J:320037
Cellular Component	GO:0033276	transcription factor TFTC complex	NAS	J:320038
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0016578	histone deubiquitination	ISO	J:164563
Biological Process	GO:0043966	histone H3 acetylation	ISO	J:164563
Biological Process	GO:0043966	histone H3 acetylation	NAS	J:320036
Biological Process	GO:0035521	monoubiquitinated histone deubiquitination	ISO	J:164563
Biological Process	GO:0035522	monoubiquitinated histone H2A deubiquitination	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	NAS	J:320111
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0016579	protein deubiquitination	ISO	J:164563
Biological Process	GO:0016579	protein deubiquitination	IDA	J:105884
Biological Process	GO:0006508	proteolysis	IEA	J:60000
Biological Process	GO:0006282	regulation of DNA repair	NAS	J:320036
Biological Process	GO:0006282	regulation of DNA repair	NAS	J:320001
Biological Process	GO:0043484	regulation of RNA splicing	NAS	J:320036
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IC	J:105884