GO Annotations Graph

• Symbol: Sgpp1
• Name: sphingosine-1-phosphate phosphatase 1
• ID: MGI:2135760

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042392	sphingosine-1-phosphate phosphatase activity	ISO	J:164563
Molecular Function	GO:0042392	sphingosine-1-phosphate phosphatase activity	IBA	J:265628
Molecular Function	GO:0042392	sphingosine-1-phosphate phosphatase activity	IDA	J:68325
Molecular Function	GO:0042392	sphingosine-1-phosphate phosphatase activity	IDA	J:79001
Molecular Function	GO:0042392	sphingosine-1-phosphate phosphatase activity	IDA	J:75337
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:79001
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IBA	J:265628
Cellular Component	GO:0016020	membrane	IDA	J:68325
Cellular Component	GO:0016020	membrane	IDA	J:75337
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0035621	ER to Golgi ceramide transport	ISO	J:164563
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	IDA	J:79001
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	IDA	J:68325
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0046839	phospholipid dephosphorylation	IBA	J:265628
Biological Process	GO:0045682	regulation of epidermis development	IMP	J:199597
Biological Process	GO:0045616	regulation of keratinocyte differentiation	IMP	J:199597
Biological Process	GO:0006668	sphinganine-1-phosphate metabolic process	IDA	J:75337
Biological Process	GO:0006668	sphinganine-1-phosphate metabolic process	IDA	J:68325
Biological Process	GO:0006665	sphingolipid metabolic process	IDA	J:68325
Biological Process	GO:0006665	sphingolipid metabolic process	IDA	J:79001
Biological Process	GO:0006670	sphingosine metabolic process	IBA	J:265628
Biological Process	GO:0006670	sphingosine metabolic process	IDA	J:75337