GO Annotations Graph

• Symbol: Dnaja3
• Name: DnaJ heat shock protein family (Hsp40) member A3
• ID: MGI:1933786

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0030695	GTPase regulator activity	IDA	J:68871
Molecular Function	GO:0031072	heat shock protein binding	IEA	J:72247
Molecular Function	GO:0030544	Hsp70 protein binding	ISO	J:155856
Molecular Function	GO:0106137	IkappaB kinase complex binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0051059	NF-kappaB binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:104462
Molecular Function	GO:0005515	protein binding	IPI	J:89091
Molecular Function	GO:0005515	protein binding	IPI	J:104462
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	IBA	J:265628
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0030971	receptor tyrosine kinase binding	IPI	J:145549
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0005133	type II interferon receptor binding	ISO	J:164563
Molecular Function	GO:0051082	unfolded protein binding	IPI	J:68871
Cellular Component	GO:0005884	actin filament	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:145549
Cellular Component	GO:0005829	cytosol	IDA	J:68871
Cellular Component	GO:0019897	extrinsic component of plasma membrane	IDA	J:145549
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005759	mitochondrial matrix	ISO	J:164563
Cellular Component	GO:0005759	mitochondrial matrix	ISO	J:164563
Cellular Component	GO:0042645	mitochondrial nucleoid	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	IDA	J:68871
Cellular Component	GO:0005739	mitochondrion	IMP	J:89091
Cellular Component	GO:0005739	mitochondrion	IDA	J:104462
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:145549
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:68871
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:145549
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0006924	activation-induced cell death of T cells	IMP	J:98985
Biological Process	GO:0006915	apoptotic process	IMP	J:104462
Biological Process	GO:0090398	cellular senescence	IDA	J:95113
Biological Process	GO:0009790	embryo development	IMP	J:89091
Biological Process	GO:0009790	embryo development	IMP	J:104462
Biological Process	GO:0006264	mitochondrial DNA replication	IMP	J:104462
Biological Process	GO:0007005	mitochondrion organization	IBA	J:265628
Biological Process	GO:0007005	mitochondrion organization	IMP	J:104462
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	IBA	J:265628
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	ISO	J:95113
Biological Process	GO:0043069	negative regulation of programmed cell death	IMP	J:89091
Biological Process	GO:0006469	negative regulation of protein kinase activity	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0060336	negative regulation of type II interferon-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0007528	neuromuscular junction development	IMP	J:145549
Biological Process	GO:0007528	neuromuscular junction development	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0031398	positive regulation of protein ubiquitination	ISO	J:164563
Biological Process	GO:0042102	positive regulation of T cell proliferation	IMP	J:98985
Biological Process	GO:0006457	protein folding	ISO	J:164563
Biological Process	GO:0050821	protein stabilization	ISO	J:164563
Biological Process	GO:0009408	response to heat	IEA	J:72247
Biological Process	GO:0034341	response to type II interferon	ISO	J:164563
Biological Process	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	IMP	J:145549
Biological Process	GO:0007264	small GTPase mediated signal transduction	IDA	J:68871
Biological Process	GO:0033077	T cell differentiation in thymus	IMP	J:98985