GO Annotations Graph

• Symbol: Trim2
• Name: tripartite motif-containing 2
• ID: MGI:1933163

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0017022	myosin binding	NAS	J:68594
Molecular Function	GO:0005515	protein binding	IPI	J:140337
Molecular Function	GO:0005515	protein binding	IPI	J:177231
Molecular Function	GO:0005515	protein binding	IPI	J:68594
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0030371	translation repressor activity	IBA	J:265628
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IBA	J:265628
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IDA	J:140337
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IDA	J:177231
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	IDA	J:177231
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	IDA	J:140337
Molecular Function	GO:0008270	zinc ion binding	NAS	J:68594
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	NAS	J:68594
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0017148	negative regulation of translation	IBA	J:265628
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IBA	J:265628
Biological Process	GO:0000209	protein polyubiquitination	IBA	J:265628
Biological Process	GO:0043523	regulation of neuron apoptotic process	IMP	J:140337
Biological Process	GO:0043523	regulation of neuron apoptotic process	ISO	J:155856