GO Annotations Graph

• Symbol: Tmem108
• Name: transmembrane protein 108
• ID: MGI:1932411

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:239183
Molecular Function	GO:0005515	protein binding	IPI	J:239200
Molecular Function	GO:0005515	protein binding	IPI	J:119738
Cellular Component	GO:0030424	axon	IDA	J:239200
Cellular Component	GO:0030424	axon	IDA	J:119738
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005769	early endosome	IDA	J:239200
Cellular Component	GO:0005769	early endosome	IBA	J:265628
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0010008	endosome membrane	IDA	J:119738
Cellular Component	GO:0010008	endosome membrane	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0014069	postsynaptic density	IDA	J:239156
Cellular Component	GO:0014069	postsynaptic density	IBA	J:265628
Cellular Component	GO:0036477	somatodendritic compartment	IDA	J:239200
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	IMP	J:239183
Biological Process	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	IMP	J:239200
Biological Process	GO:0097484	dendrite extension	IMP	J:239183
Biological Process	GO:0097484	dendrite extension	IMP	J:239200
Biological Process	GO:0097484	dendrite extension	IBA	J:265628
Biological Process	GO:0021542	dentate gyrus development	IMP	J:239156
Biological Process	GO:0098815	modulation of excitatory postsynaptic potential	IMP	J:239156
Biological Process	GO:0031175	neuron projection development	IMP	J:239183
Biological Process	GO:0031175	neuron projection development	IMP	J:239200
Biological Process	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway	IMP	J:239183
Biological Process	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway	IMP	J:239200
Biological Process	GO:0097106	postsynaptic density organization	IMP	J:239156
Biological Process	GO:0097106	postsynaptic density organization	IBA	J:265628
Biological Process	GO:0006898	receptor-mediated endocytosis	IMP	J:239183
Biological Process	GO:0008090	retrograde axonal transport	IDA	J:119738
Biological Process	GO:0008090	retrograde axonal transport	IBA	J:265628