GO Annotations Graph

• Symbol: Piwil1
• Name: piwi-like RNA-mediated gene silencing 1
• ID: MGI:1928897

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004519	endonuclease activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0003729	mRNA binding	IDA	J:77015
Molecular Function	GO:0003729	mRNA binding	IDA	J:112901
Molecular Function	GO:0140262	mRNA cap binding complex binding	IDA	J:112901
Molecular Function	GO:0004518	nuclease activity	IEA	J:60000
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0034584	piRNA binding	IDA	J:148066
Molecular Function	GO:0034584	piRNA binding	IDA	J:110212
Molecular Function	GO:0034584	piRNA binding	IDA	J:243444
Molecular Function	GO:0034584	piRNA binding	IDA	J:193401
Molecular Function	GO:0034584	piRNA binding	IDA	J:112901
Molecular Function	GO:0034584	piRNA binding	IDA	J:242565
Molecular Function	GO:0034584	piRNA binding	ISO	J:164563
Molecular Function	GO:0034584	piRNA binding	IBA	J:265628
Molecular Function	GO:1905538	polysome binding	IDA	J:112901
Molecular Function	GO:0005515	protein binding	IPI	J:152071
Molecular Function	GO:0005515	protein binding	IPI	J:112036
Molecular Function	GO:0005515	protein binding	IPI	J:193401
Molecular Function	GO:0005515	protein binding	IPI	J:112901
Molecular Function	GO:0005515	protein binding	IPI	J:242565
Molecular Function	GO:0005515	protein binding	IPI	J:148942
Molecular Function	GO:0005515	protein binding	IPI	J:197673
Molecular Function	GO:0005515	protein binding	IPI	J:110342
Molecular Function	GO:0005515	protein binding	IPI	J:161125
Molecular Function	GO:0005515	protein binding	IPI	J:243444
Molecular Function	GO:0005515	protein binding	IPI	J:189932
Molecular Function	GO:0005515	protein binding	IPI	J:155574
Molecular Function	GO:0005515	protein binding	IPI	J:165503
Molecular Function	GO:0019901	protein kinase binding	IPI	J:205033
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0004521	RNA endonuclease activity	IMP	J:182800
Molecular Function	GO:0004521	RNA endonuclease activity	IBA	J:265628
Molecular Function	GO:0003727	single-stranded RNA binding	IDA	J:77015
Molecular Function	GO:0003727	single-stranded RNA binding	IDA	J:71909
Cellular Component	GO:0033391	chromatoid body	IDA	J:110342
Cellular Component	GO:0033391	chromatoid body	IDA	J:112901
Cellular Component	GO:0033391	chromatoid body	IDA	J:173639
Cellular Component	GO:0005737	cytoplasm	IDA	J:242565
Cellular Component	GO:0005737	cytoplasm	IDA	J:71909
Cellular Component	GO:0005737	cytoplasm	IDA	J:173639
Cellular Component	GO:0005737	cytoplasm	IDA	J:77015
Cellular Component	GO:0005737	cytoplasm	IDA	J:156954
Cellular Component	GO:0005737	cytoplasm	IDA	J:87735
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5605344
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5615685
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5629239
Cellular Component	GO:0097433	dense body	IDA	J:173639
Cellular Component	GO:0005634	nucleus	IDA	J:173639
Cellular Component	GO:0043186	P granule	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0051321	meiotic cell cycle	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0010529	negative regulation of transposition	IMP	J:182800
Biological Process	GO:0000239	pachytene	IGI	J:173639
Biological Process	GO:0000239	pachytene	IMP	J:173639
Biological Process	GO:0034587	piRNA processing	IMP	J:110212
Biological Process	GO:0034587	piRNA processing	IMP	J:182800
Biological Process	GO:0006417	regulation of translation	NAS	J:112901
Biological Process	GO:0031047	RNA-mediated gene silencing	IBA	J:265628
Biological Process	GO:0035092	sperm DNA condensation	IMP	J:242565
Biological Process	GO:0007286	spermatid development	ISO	J:164563
Biological Process	GO:0007286	spermatid development	IMP	J:77015
Biological Process	GO:0007286	spermatid development	IMP	J:242565
Biological Process	GO:0007283	spermatogenesis	IDA	J:193401
Biological Process	GO:0007283	spermatogenesis	IMP	J:242565
Biological Process	GO:0007283	spermatogenesis	IMP	J:182800
Biological Process	GO:0007283	spermatogenesis	IMP	J:77015