GO Annotations Graph

• Symbol: Trpv6
• Name: transient receptor potential cation channel, subfamily V, member 6
• ID: MGI:1927259

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005262	calcium channel activity	ISO	J:155856
Molecular Function	GO:0005262	calcium channel activity	ISO	J:164563
Molecular Function	GO:0005262	calcium channel activity	IMP	J:113972
Molecular Function	GO:0005262	calcium channel activity	IBA	J:265628
Molecular Function	GO:0005262	calcium channel activity	IDA	J:78617
Molecular Function	GO:0005516	calmodulin binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	IPI	J:113972
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:113972
Cellular Component	GO:0034704	calcium channel complex	IDA	J:113972
Cellular Component	GO:0016020	membrane	ISS	J:78617
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0055074	calcium ion homeostasis	IMP	J:192782
Biological Process	GO:0055074	calcium ion homeostasis	IMP	J:133151
Biological Process	GO:0070509	calcium ion import	ISO	J:155856
Biological Process	GO:0098703	calcium ion import across plasma membrane	ISO	J:155856
Biological Process	GO:0098703	calcium ion import across plasma membrane	IMP	J:192782
Biological Process	GO:0098703	calcium ion import across plasma membrane	ISO	J:164563
Biological Process	GO:0098703	calcium ion import across plasma membrane	IBA	J:265628
Biological Process	GO:0070588	calcium ion transmembrane transport	ISO	J:155856
Biological Process	GO:0070588	calcium ion transmembrane transport	IMP	J:113972
Biological Process	GO:0070588	calcium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0006816	calcium ion transport	ISO	J:164563
Biological Process	GO:0006816	calcium ion transport	IDA	J:78617
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0035898	parathyroid hormone secretion	IMP	J:133151
Biological Process	GO:0051289	protein homotetramerization	ISO	J:155856
Biological Process	GO:0051592	response to calcium ion	IDA	J:192782
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247