GO Annotations Graph

• Symbol: Ppp2r1a
• Name: protein phosphatase 2, regulatory subunit A, alpha
• ID: MGI:1926334

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:1990405	protein antigen binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:154173
Molecular Function	GO:0005515	protein binding	IPI	J:124164
Molecular Function	GO:0005515	protein binding	IPI	J:266118
Molecular Function	GO:0005515	protein binding	IPI	J:201565
Molecular Function	GO:0005515	protein binding	IPI	J:141034
Molecular Function	GO:0005515	protein binding	IPI	J:85463
Molecular Function	GO:0005515	protein binding	IPI	J:141034
Molecular Function	GO:0005515	protein binding	IPI	J:141034
Molecular Function	GO:0005515	protein binding	IPI	J:193640
Molecular Function	GO:0005515	protein binding	IPI	J:84681
Molecular Function	GO:0005515	protein binding	IPI	J:116445
Molecular Function	GO:0005515	protein binding	IPI	J:84681
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0019888	protein phosphatase regulator activity	IBA	J:265628
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	IDA	J:85463
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000775	chromosome, centromeric region	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-209096
Cellular Component	GO:0005829	cytosol	IDA	J:84681
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:206458
Cellular Component	GO:0098978	glutamatergic synapse	EXP	J:206458
Cellular Component	GO:0016328	lateral plasma membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0000159	protein phosphatase type 2A complex	ISO	J:164563
Cellular Component	GO:0000159	protein phosphatase type 2A complex	IBA	J:265628
Cellular Component	GO:0000159	protein phosphatase type 2A complex	IDA	J:116445
Cellular Component	GO:0045202	synapse	EXP	J:263376
Cellular Component	GO:0045202	synapse	IDA	J:263376
Cellular Component	GO:0045202	synapse	EXP	J:206458
Cellular Component	GO:0045202	synapse	IDA	J:206458
Biological Process	GO:0007059	chromosome segregation	ISO	J:164563
Biological Process	GO:0007059	chromosome segregation	IBA	J:265628
Biological Process	GO:0007143	female meiotic nuclear division	IMP	J:213800
Biological Process	GO:0051754	meiotic sister chromatid cohesion, centromeric	IMP	J:213800
Biological Process	GO:0051232	meiotic spindle elongation	IMP	J:213800
Biological Process	GO:0051306	mitotic sister chromatid separation	IMP	J:213800
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	IMP	J:259480
Biological Process	GO:0070262	peptidyl-serine dephosphorylation	IDA	J:85463
Biological Process	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	IMP	J:85463
Biological Process	GO:0006470	protein dephosphorylation	IBA	J:265628
Biological Process	GO:0065003	protein-containing complex assembly	IEA	J:72247
Biological Process	GO:1903538	regulation of meiotic cell cycle process involved in oocyte maturation	IMP	J:213800
Biological Process	GO:0043029	T cell homeostasis	IMP	J:259480