GO Annotations Graph

• Symbol: Hook1
• Name: hook microtubule tethering protein 1
• ID: MGI:1925213

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IDA	J:90042
Molecular Function	GO:0051959	dynein light intermediate chain binding	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0008017	microtubule binding	IBA	J:265628
Molecular Function	GO:0008017	microtubule binding	IDA	J:90042
Molecular Function	GO:0008017	microtubule binding	ISO	J:77010
Molecular Function	GO:0005515	protein binding	IPI	J:241007
Molecular Function	GO:0005515	protein binding	IPI	J:277903
Molecular Function	GO:0005515	protein binding	IPI	J:144218
Molecular Function	GO:0005515	protein binding	IPI	J:90042
Molecular Function	GO:0005515	protein binding	IPI	J:97449
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:0005813	centrosome	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0070695	FHF complex	ISO	J:164563
Cellular Component	GO:0030897	HOPS complex	ISO	J:164563
Cellular Component	GO:0005874	microtubule	IEA	J:60000
Cellular Component	GO:0015630	microtubule cytoskeleton	IDA	J:77010
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0031122	cytoplasmic microtubule organization	IBA	J:265628
Biological Process	GO:0031122	cytoplasmic microtubule organization	IMP	J:108463
Biological Process	GO:0030705	cytoskeleton-dependent intracellular transport	IBA	J:265628
Biological Process	GO:0045022	early endosome to late endosome transport	ISO	J:164563
Biological Process	GO:0007032	endosome organization	ISO	J:164563
Biological Process	GO:0008333	endosome to lysosome transport	ISO	J:164563
Biological Process	GO:0007030	Golgi organization	IMP	J:108463
Biological Process	GO:0007040	lysosome organization	ISO	J:164563
Biological Process	GO:1905198	manchette assembly	IMP	J:89468
Biological Process	GO:1905198	manchette assembly	IMP	J:108463
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:1905719	protein localization to perinuclear region of cytoplasm	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0007286	spermatid development	IMP	J:77010
Biological Process	GO:0007283	spermatogenesis	IEA	J:60000