Mtmr2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Mtmr2
myotubularin related protein 2
MGI:1924366

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	IPI	J:106780
Molecular Function	GO:0016791	phosphatase activity	IEA	J:72247
Molecular Function	GO:0052866	phosphatidylinositol phosphate phosphatase activity	IMP	J:177998
Molecular Function	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	ISO	J:164563
Molecular Function	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	IBA	J:265628
Molecular Function	GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:106780
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:84578
Cellular Component	GO:0005737	cytoplasm	IDA	J:106780
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-6809875
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-6809916
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-6809945
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-6809977
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-NUL-6810026
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0097060	synaptic membrane	ISO	J:155856
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Cellular Component	GO:0005774	vacuolar membrane	IDA	J:106780
Biological Process	GO:0097062	dendritic spine maintenance	ISO	J:155856
Biological Process	GO:0016311	dephosphorylation	IDA	J:106780
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0032288	myelin assembly	IGI	J:177998
Biological Process	GO:0032288	myelin assembly	IMP	J:177998
Biological Process	GO:0032288	myelin assembly	IGI	J:177998
Biological Process	GO:0032288	myelin assembly	IMP	J:177998
Biological Process	GO:0032288	myelin assembly	IGI	J:177998
Biological Process	GO:0042552	myelination	IGI	J:177998
Biological Process	GO:0045806	negative regulation of endocytosis	ISO	J:155856
Biological Process	GO:0090394	negative regulation of excitatory postsynaptic potential	ISO	J:155856
Biological Process	GO:0031642	negative regulation of myelination	IMP	J:151079
Biological Process	GO:0031642	negative regulation of myelination	IGI	J:177998
Biological Process	GO:2000645	negative regulation of receptor catabolic process	ISO	J:155856
Biological Process	GO:0002091	negative regulation of receptor internalization	ISO	J:155856
Biological Process	GO:0048666	neuron development	IGI	J:177998
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	ISO	J:164563
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	IDA	J:106780
Biological Process	GO:0046488	phosphatidylinositol metabolic process	IMP	J:177998
Biological Process	GO:0046488	phosphatidylinositol metabolic process	IMP	J:177998
Biological Process	GO:2000643	positive regulation of early endosome to late endosome transport	ISO	J:155856
Biological Process	GO:0060304	regulation of phosphatidylinositol dephosphorylation	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23