GO Annotations Graph

• Symbol: Senp2
• Name: SUMO/sentrin specific peptidase 2
• ID: MGI:1923076

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008234	cysteine-type peptidase activity	IEA	J:60000
Molecular Function	GO:0008234	cysteine-type peptidase activity	IEA	J:72247
Molecular Function	GO:0016929	deSUMOylase activity	IDA	J:84904
Molecular Function	GO:0016929	deSUMOylase activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0070139	SUMO-specific endopeptidase activity	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016604	nuclear body	IDA	J:162938
Cellular Component	GO:0005643	nuclear pore	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0016605	PML body	IDA	J:84904
Biological Process	GO:0009950	dorsal/ventral axis specification	ISO	J:155856
Biological Process	GO:0045444	fat cell differentiation	IDA	J:161702
Biological Process	GO:0007507	heart development	IMP	J:162938
Biological Process	GO:0060711	labyrinthine layer development	IMP	J:144707
Biological Process	GO:0051028	mRNA transport	IEA	J:60000
Biological Process	GO:0035562	negative regulation of chromatin binding	IMP	J:162938
Biological Process	GO:0032091	negative regulation of protein binding	ISO	J:155856
Biological Process	GO:0031397	negative regulation of protein ubiquitination	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:0031398	positive regulation of protein ubiquitination	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:162938
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:162938
Biological Process	GO:0031648	protein destabilization	ISO	J:164563
Biological Process	GO:0016926	protein desumoylation	IDA	J:161702
Biological Process	GO:0016926	protein desumoylation	IDA	J:84904
Biological Process	GO:0016926	protein desumoylation	ISO	J:164563
Biological Process	GO:0016926	protein desumoylation	IBA	J:265628
Biological Process	GO:0016926	protein desumoylation	IMP	J:162938
Biological Process	GO:0016926	protein desumoylation	IDA	J:97581
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0006508	proteolysis	IEA	J:72247
Biological Process	GO:0006508	proteolysis	IEA	J:60000
Biological Process	GO:0032875	regulation of DNA endoreduplication	IMP	J:144707
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	IMP	J:144707
Biological Process	GO:0051246	regulation of protein metabolic process	ISO	J:155856
Biological Process	GO:0060712	spongiotrophoblast layer development	IMP	J:144707
Biological Process	GO:0060707	trophoblast giant cell differentiation	IMP	J:144707
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000