GO Annotations Graph

• Symbol: Auts2
• Name: autism susceptibility candidate 2
• ID: MGI:1919847

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:73065
Molecular Function	GO:0005515	protein binding	IPI	J:322808
Molecular Function	GO:0005515	protein binding	IPI	J:217675
Cellular Component	GO:0015629	actin cytoskeleton	IDA	J:243531
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0030426	growth cone	IDA	J:243531
Cellular Component	GO:0005634	nucleus	IDA	J:155881
Cellular Component	GO:0005634	nucleus	IDA	J:243531
Cellular Component	GO:0005634	nucleus	IDA	J:217675
Biological Process	GO:0031532	actin cytoskeleton reorganization	IMP	J:243531
Biological Process	GO:0048675	axon extension	IMP	J:243531
Biological Process	GO:0097484	dendrite extension	IMP	J:243531
Biological Process	GO:0098582	innate vocalization behavior	IMP	J:217675
Biological Process	GO:0001764	neuron migration	IMP	J:243531
Biological Process	GO:0051571	positive regulation of histone H3-K4 methylation	ISO	J:73065
Biological Process	GO:2000620	positive regulation of histone H4-K16 acetylation	ISO	J:73065
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	IMP	J:243531
Biological Process	GO:0035022	positive regulation of Rac protein signal transduction	IMP	J:243531
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0060013	righting reflex	IMP	J:217675