GO Annotations Graph

• Symbol: Rcc2
• Name: regulator of chromosome condensation 2
• ID: MGI:1919784

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IEA	J:60000
Molecular Function	GO:0008017	microtubule binding	ISO	J:164563
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0031267	small GTPase binding	ISO	J:164563
Molecular Function	GO:0031267	small GTPase binding	IPI	J:219617
Molecular Function	GO:0031267	small GTPase binding	IBA	J:265628
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0034506	chromosome, centromeric core domain	ISO	J:164563
Cellular Component	GO:0000775	chromosome, centromeric region	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0031901	early endosome membrane	IDA	J:219617
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0005874	microtubule	IEA	J:60000
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:1990023	mitotic spindle midzone	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:219617
Cellular Component	GO:0005886	plasma membrane	IDA	J:219617
Biological Process	GO:0090630	activation of GTPase activity	IGI	J:219617
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0072356	chromosome passenger complex localization to kinetochore	ISO	J:164563
Biological Process	GO:0045184	establishment of protein localization	IGI	J:219617
Biological Process	GO:0048041	focal adhesion assembly	ISO	J:164563
Biological Process	GO:0007229	integrin-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0051895	negative regulation of focal adhesion assembly	IMP	J:206561
Biological Process	GO:0034260	negative regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0034260	negative regulation of GTPase activity	IMP	J:219617
Biological Process	GO:0034260	negative regulation of GTPase activity	IMP	J:206561
Biological Process	GO:0034260	negative regulation of GTPase activity	IBA	J:265628
Biological Process	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	IMP	J:206561
Biological Process	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore	ISO	J:164563
Biological Process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0030334	regulation of cell migration	IMP	J:206561
Biological Process	GO:0010762	regulation of fibroblast migration	IMP	J:219617
Biological Process	GO:1900027	regulation of ruffle assembly	IGI	J:219617
Biological Process	GO:1900027	regulation of ruffle assembly	IMP	J:219617