GO Annotations Graph

• Symbol: Smyd2
• Name: SET and MYND domain containing 2
• ID: MGI:1915889

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	IDA	J:169899
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	IDA	J:189874
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	IEA	J:72245
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:0002039	p53 binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:158898
Molecular Function	GO:0005515	protein binding	IPI	J:245303
Molecular Function	GO:0005515	protein binding	IPI	J:169899
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	ISO	J:164563
Molecular Function	GO:0000993	RNA polymerase II complex binding	IDA	J:158898
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:169899
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IDA	J:158898
Cellular Component	GO:0005634	nucleus	IDA	J:158898
Cellular Component	GO:0005634	nucleus	IDA	J:169899
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0034968	histone lysine methylation	IBA	J:265628
Biological Process	GO:0016570	histone modification	IDA	J:189874
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0008285	negative regulation of cell population proliferation	IDA	J:169899
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0018027	peptidyl-lysine dimethylation	IDA	J:169899
Biological Process	GO:0018026	peptidyl-lysine monomethylation	ISO	J:164563
Biological Process	GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	ISO	J:164563