GO Annotations Graph

• Symbol: Laptm4b
• Name: lysosomal-associated protein transmembrane 4B
• ID: MGI:1890494

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0097001	ceramide binding	ISO	J:164563
Molecular Function	GO:0019900	kinase binding	ISO	J:164563
Molecular Function	GO:1902936	phosphatidylinositol bisphosphate binding	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0042995	cell projection	ISO	J:164563
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005768	endosome	ISO	J:164563
Cellular Component	GO:0031902	late endosome membrane	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	IBA	J:265628
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0032585	multivesicular body membrane	ISO	J:164563
Cellular Component	GO:0097487	multivesicular body, internal vesicle	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0007032	endosome organization	ISO	J:164563
Biological Process	GO:0032509	endosome transport via multivesicular body sorting pathway	ISO	J:164563
Biological Process	GO:1905166	negative regulation of lysosomal protein catabolic process	ISO	J:164563
Biological Process	GO:0032911	negative regulation of transforming growth factor beta1 production	ISO	J:164563
Biological Process	GO:0097213	regulation of lysosomal membrane permeability	ISO	J:164563
Biological Process	GO:1905671	regulation of lysosome organization	ISO	J:164563