GO Annotations Graph

• Symbol: Suv39h2
• Name: suppressor of variegation 3-9 2
• ID: MGI:1890396

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:65972
Molecular Function	GO:0140938	histone H3 methyltransferase activity	IDA	J:75203
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	ISO	J:164563
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	IBA	J:265628
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	IGI	J:100751
Molecular Function	GO:0140949	histone H3K9 trimethyltransferase activity	IEA	J:72245
Molecular Function	GO:0140947	histone H3K9me2 methyltransferase activity	IGI	J:196057
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:210023
Molecular Function	GO:0008276	protein methyltransferase activity	IDA	J:65972
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:173973
Molecular Function	GO:1904047	S-adenosyl-L-methionine binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:210023
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000775	chromosome, centromeric region	IEA	J:60000
Cellular Component	GO:0000792	heterochromatin	IDA	J:65972
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:173973
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0071456	cellular response to hypoxia	ISO	J:173973
Biological Process	GO:0006325	chromatin organization	ISO	J:164563
Biological Process	GO:0006338	chromatin remodeling	ISO	J:164563
Biological Process	GO:0007623	circadian rhythm	IMP	J:210023
Biological Process	GO:0034968	histone lysine methylation	IBA	J:265628
Biological Process	GO:0007140	male meiotic nuclear division	IEP	J:65972
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:210023
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	IMP	J:210023
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:173973
Biological Process	GO:0048511	rhythmic process	IEA	J:60000