GO Annotations Graph

• Symbol: Crtam
• Name: cytotoxic and regulatory T cell molecule
• ID: MGI:1859822

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:145314
Molecular Function	GO:0005102	signaling receptor binding	IPI	J:114711
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	ISS	J:114711
Molecular Function	GO:0005102	signaling receptor binding	IBA	J:265628
Cellular Component	GO:0001772	immunological synapse	IDA	J:145314
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:212409
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISS	J:114711
Cellular Component	GO:0005886	plasma membrane	IDA	J:114711
Cellular Component	GO:0005886	plasma membrane	IDA	J:152770
Cellular Component	GO:0005886	plasma membrane	IDA	J:145314
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISS	J:62065
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0008037	cell recognition	ISO	J:164563
Biological Process	GO:0008037	cell recognition	IDA	J:114711
Biological Process	GO:0008037	cell recognition	ISS	J:114711
Biological Process	GO:0008037	cell recognition	IBA	J:265628
Biological Process	GO:0051606	detection of stimulus	ISO	J:164563
Biological Process	GO:0051606	detection of stimulus	ISS	J:114711
Biological Process	GO:0051606	detection of stimulus	IDA	J:114711
Biological Process	GO:0002355	detection of tumor cell	IDA	J:114711
Biological Process	GO:0002355	detection of tumor cell	ISO	J:164563
Biological Process	GO:0002355	detection of tumor cell	ISS	J:114711
Biological Process	GO:0002355	detection of tumor cell	IBA	J:265628
Biological Process	GO:0001768	establishment of T cell polarity	IDA	J:145314
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IMP	J:152770
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IMP	J:212409
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0097021	lymphocyte migration into lymphoid organs	IMP	J:212409
Biological Process	GO:0046007	negative regulation of activated T cell proliferation	IMP	J:145314
Biological Process	GO:0001819	positive regulation of cytokine production	ISO	J:164563
Biological Process	GO:0001819	positive regulation of cytokine production	ISS	J:114711
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	ISO	J:164563
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	IDA	J:114711
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	ISS	J:114711
Biological Process	GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	IDA	J:114711
Biological Process	GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	ISS	J:114711
Biological Process	GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	ISO	J:164563
Biological Process	GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	IBA	J:265628
Biological Process	GO:0032729	positive regulation of type II interferon production	IMP	J:145314
Biological Process	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	IMP	J:152770
Biological Process	GO:0050863	regulation of T cell activation	IMP	J:212409
Biological Process	GO:0045580	regulation of T cell differentiation	IMP	J:212409