GO Annotations Graph

• Symbol: Ccdc22
• Name: coiled-coil domain containing 22
• ID: MGI:1859608

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0097602	cullin family protein binding	ISO	J:164563
Molecular Function	GO:0097602	cullin family protein binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:177167
Molecular Function	GO:0005515	protein binding	IPI	J:177167
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005768	endosome	IEA	J:60000
Biological Process	GO:0042632	cholesterol homeostasis	ISO	J:236595
Biological Process	GO:0007253	cytoplasmic sequestering of NF-kappaB	ISO	J:164563
Biological Process	GO:0032456	endocytic recycling	ISO	J:164563
Biological Process	GO:0006893	Golgi to plasma membrane transport	ISO	J:164563
Biological Process	GO:0006878	intracellular copper ion homeostasis	ISO	J:164563
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	IBA	J:265628
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0097006	regulation of plasma lipoprotein particle levels	ISO	J:236595