GO Annotations Graph

• Symbol: Syt11
• Name: synaptotagmin XI
• ID: MGI:1859547

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0048487	beta-tubulin binding	IPI	J:211330
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	IBA	J:265628
Molecular Function	GO:0030276	clathrin binding	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	IPI	J:232984
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0001786	phosphatidylserine binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:274868
Molecular Function	GO:0005515	protein binding	IPI	J:211330
Molecular Function	GO:0005515	protein binding	IPI	J:211330
Molecular Function	GO:0005515	protein binding	IPI	J:211330
Molecular Function	GO:0000149	SNARE binding	IPI	J:211330
Molecular Function	GO:0000149	SNARE binding	IPI	J:211330
Molecular Function	GO:0000149	SNARE binding	IBA	J:265628
Molecular Function	GO:0031369	translation initiation factor binding	IPI	J:211330
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0044297	cell body	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:193251
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0030425	dendrite	IDA	J:274868
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0098691	dopaminergic synapse	IDA	J:260099
Cellular Component	GO:0098691	dopaminergic synapse	IDA	J:260099
Cellular Component	GO:0098691	dopaminergic synapse	IDA	J:260099
Cellular Component	GO:0098691	dopaminergic synapse	IMP	J:260099
Cellular Component	GO:0098691	dopaminergic synapse	IMP	J:260099
Cellular Component	GO:0032009	early phagosome	IDA	J:244524
Cellular Component	GO:0032009	early phagosome	IDA	J:193251
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0060076	excitatory synapse	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0060077	inhibitory synapse	ISO	J:155856
Cellular Component	GO:0005764	lysosome	IDA	J:244524
Cellular Component	GO:0005764	lysosome	IDA	J:193251
Cellular Component	GO:0005764	lysosome	IDA	J:233974
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0001891	phagocytic cup	IDA	J:193251
Cellular Component	GO:0045335	phagocytic vesicle	IDA	J:232982
Cellular Component	GO:0005886	plasma membrane	IDA	J:67898
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	IDA	J:274868
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0098793	presynapse	ISO	J:155856
Cellular Component	GO:0048787	presynaptic active zone membrane	ISO	J:155856
Cellular Component	GO:0048787	presynaptic active zone membrane	ISO	J:155856
Cellular Component	GO:0055037	recycling endosome	IDA	J:244524
Cellular Component	GO:0055037	recycling endosome	IDA	J:193251
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IBA	J:265628
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0043195	terminal bouton	ISO	J:155856
Cellular Component	GO:0005802	trans-Golgi network	IDA	J:244524
Cellular Component	GO:0031982	vesicle	ISO	J:155856
Cellular Component	GO:0031982	vesicle	IDA	J:274868
Biological Process	GO:0006914	autophagy	ISO	J:164563
Biological Process	GO:0006914	autophagy	IMP	J:239895
Biological Process	GO:1990927	calcium ion regulated lysosome exocytosis	IMP	J:233974
Biological Process	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter	IBA	J:265628
Biological Process	GO:0071277	cellular response to calcium ion	IBA	J:265628
Biological Process	GO:0051650	establishment of vesicle localization	IMP	J:274868
Biological Process	GO:0007612	learning	IMP	J:274868
Biological Process	GO:0007613	memory	IMP	J:274868
Biological Process	GO:1905444	negative regulation of clathrin coat assembly	ISO	J:155856
Biological Process	GO:1900186	negative regulation of clathrin-dependent endocytosis	ISO	J:155856
Biological Process	GO:0001818	negative regulation of cytokine production	IDA	J:244524
Biological Process	GO:0033602	negative regulation of dopamine secretion	IDA	J:260099
Biological Process	GO:0033602	negative regulation of dopamine secretion	ISO	J:155856
Biological Process	GO:0045806	negative regulation of endocytosis	ISO	J:155856
Biological Process	GO:0045806	negative regulation of endocytosis	IDA	J:260099
Biological Process	GO:0032715	negative regulation of interleukin-6 production	IMP	J:193251
Biological Process	GO:0032715	negative regulation of interleukin-6 production	IMP	J:232982
Biological Process	GO:0032715	negative regulation of interleukin-6 production	IDA	J:244524
Biological Process	GO:1905154	negative regulation of membrane invagination	ISO	J:155856
Biological Process	GO:1903979	negative regulation of microglial cell activation	IDA	J:244524
Biological Process	GO:0050765	negative regulation of phagocytosis	IMP	J:193251
Biological Process	GO:0050765	negative regulation of phagocytosis	IDA	J:244524
Biological Process	GO:1900243	negative regulation of synaptic vesicle endocytosis	ISO	J:155856
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	IMP	J:232982
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	IMP	J:193251
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	IDA	J:244524
Biological Process	GO:0001778	plasma membrane repair	IMP	J:233974
Biological Process	GO:1905171	positive regulation of protein localization to phagocytic vesicle	IMP	J:193251
Biological Process	GO:0017158	regulation of calcium ion-dependent exocytosis	IBA	J:265628
Biological Process	GO:1900424	regulation of defense response to bacterium	IMP	J:193251
Biological Process	GO:0014059	regulation of dopamine secretion	IBA	J:265628
Biological Process	GO:1905162	regulation of phagosome maturation	IC	J:193251
Biological Process	GO:1905162	regulation of phagosome maturation	TAS	J:232982
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:260099
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IMP	J:260099
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:260099
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IMP	J:260099
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:260099
Biological Process	GO:0009611	response to wounding	IMP	J:233974
Biological Process	GO:0006906	vesicle fusion	IBA	J:265628