GO Annotations Graph

• Symbol: Reck
• Name: reversion-inducing-cysteine-rich protein with kazal motifs
• ID: MGI:1855698

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:1904928	coreceptor activity involved in canonical Wnt signaling pathway	IDA	J:266652
Molecular Function	GO:0004866	endopeptidase inhibitor activity	IBA	J:265628
Molecular Function	GO:0004866	endopeptidase inhibitor activity	IDA	J:107674
Molecular Function	GO:0004866	endopeptidase inhibitor activity	IDA	J:107674
Molecular Function	GO:0004866	endopeptidase inhibitor activity	ISO	J:73065
Molecular Function	GO:0004866	endopeptidase inhibitor activity	IDA	J:107674
Molecular Function	GO:0008191	metalloendopeptidase inhibitor activity	ISO	J:164563
Molecular Function	GO:0030414	peptidase inhibitor activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:266652
Molecular Function	GO:0004867	serine-type endopeptidase inhibitor activity	IEA	J:60000
Molecular Function	GO:0017147	Wnt-protein binding	IPI	J:266652
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:266652
Cellular Component	GO:0005886	plasma membrane	IDA	J:256044
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:1990909	Wnt signalosome	IDA	J:266652
Biological Process	GO:0001955	blood vessel maturation	IBA	J:265628
Biological Process	GO:0001955	blood vessel maturation	IGI	J:107674
Biological Process	GO:0001955	blood vessel maturation	IGI	J:107674
Biological Process	GO:0001955	blood vessel maturation	IMP	J:107674
Biological Process	GO:0001955	blood vessel maturation	IMP	J:107674
Biological Process	GO:0007566	embryo implantation	IDA	J:140260
Biological Process	GO:0035115	embryonic forelimb morphogenesis	IMP	J:184585
Biological Process	GO:0030198	extracellular matrix organization	IBA	J:265628
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:107674
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:107674
Biological Process	GO:0030198	extracellular matrix organization	IMP	J:107674
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:164563
Biological Process	GO:1904684	negative regulation of metalloendopeptidase activity	ISO	J:164563
Biological Process	GO:1904684	negative regulation of metalloendopeptidase activity	IMP	J:223602
Biological Process	GO:1904684	negative regulation of metalloendopeptidase activity	IBA	J:265628
Biological Process	GO:0010466	negative regulation of peptidase activity	IEA	J:60000
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IDA	J:266652
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IDA	J:256044
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	ISO	J:73065
Biological Process	GO:0045765	regulation of angiogenesis	IMP	J:256044
Biological Process	GO:0090210	regulation of establishment of blood-brain barrier	IMP	J:256044
Biological Process	GO:0002040	sprouting angiogenesis	IBA	J:265628
Biological Process	GO:0016055	Wnt signaling pathway	IEA	J:60000