GO Annotations Graph

• Symbol: Slc25a4
• Name: solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
• ID: MGI:1353495

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015297	antiporter activity	IEA	J:60000
Molecular Function	GO:0005471	ATP:ADP antiporter activity	IDA	J:288657
Molecular Function	GO:0005471	ATP:ADP antiporter activity	IMP	J:287489
Molecular Function	GO:0005471	ATP:ADP antiporter activity	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	ISO	J:155856
Molecular Function	GO:0017077	oxidative phosphorylation uncoupler activity	IDA	J:288657
Molecular Function	GO:0005515	protein binding	IPI	J:287489
Molecular Function	GO:0005515	protein binding	IPI	J:168212
Molecular Function	GO:0015078	proton transmembrane transporter activity	IDA	J:288657
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0005743	mitochondrial inner membrane	ISO	J:155856
Cellular Component	GO:0005743	mitochondrial inner membrane	ISO	J:164563
Cellular Component	GO:0005743	mitochondrial inner membrane	HDA	J:100953
Cellular Component	GO:0005743	mitochondrial inner membrane	ISS	J:137567
Cellular Component	GO:0005741	mitochondrial outer membrane	ISS	J:137567
Cellular Component	GO:0005757	mitochondrial permeability transition pore complex	IMP	J:287067
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Biological Process	GO:1990845	adaptive thermogenesis	IMP	J:288657
Biological Process	GO:0015866	ADP transport	ISO	J:164563
Biological Process	GO:0008637	apoptotic mitochondrial changes	IGI	J:133172
Biological Process	GO:0008637	apoptotic mitochondrial changes	IGI	J:133172
Biological Process	GO:0140021	mitochondrial ADP transmembrane transport	IDA	J:288657
Biological Process	GO:0140021	mitochondrial ADP transmembrane transport	ISO	J:164563
Biological Process	GO:0140021	mitochondrial ADP transmembrane transport	IMP	J:287489
Biological Process	GO:1990544	mitochondrial ATP transmembrane transport	IMP	J:287489
Biological Process	GO:1990544	mitochondrial ATP transmembrane transport	IDA	J:288657
Biological Process	GO:1990544	mitochondrial ATP transmembrane transport	ISO	J:164563
Biological Process	GO:0010667	negative regulation of cardiac muscle cell apoptotic process	ISO	J:155856
Biological Process	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process	ISO	J:155856
Biological Process	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	IBA	J:265628
Biological Process	GO:0060546	negative regulation of necroptotic process	ISO	J:164563
Biological Process	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	ISO	J:155856
Biological Process	GO:1901526	positive regulation of mitophagy	IDA	J:287489
Biological Process	GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	ISO	J:155856
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	IMP	J:287067
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247