Nr1h2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Nr1h2
nuclear receptor subfamily 1, group H, member 2
MGI:1352463

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0034191	apolipoprotein A-I receptor binding	ISO	J:164563
Molecular Function	GO:0051117	ATPase binding	ISO	J:164563
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:264834
Molecular Function	GO:0003677	DNA binding	IDA	J:89079
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:155856
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IGI	J:23077
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:89079
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004879	nuclear receptor activity	IBA	J:265628
Molecular Function	GO:0004879	nuclear receptor activity	IDA	J:89079
Molecular Function	GO:0046965	nuclear retinoid X receptor binding	ISO	J:155856
Molecular Function	GO:0046965	nuclear retinoid X receptor binding	IDA	J:23077
Molecular Function	GO:0005515	protein binding	IPI	J:134888
Molecular Function	GO:0005515	protein binding	IPI	J:200990
Molecular Function	GO:0005515	protein binding	IPI	J:200990
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:142844
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0044255	cellular lipid metabolic process	IDA	J:89079
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:206917
Biological Process	GO:0042632	cholesterol homeostasis	IDA	J:123957
Biological Process	GO:0006351	DNA-templated transcription	IDA	J:89079
Biological Process	GO:0055088	lipid homeostasis	IMP	J:142844
Biological Process	GO:0006629	lipid metabolic process	IEA	J:72247
Biological Process	GO:0010887	negative regulation of cholesterol storage	ISO	J:164563
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	IGI	J:262347
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:155856
Biological Process	GO:0032369	negative regulation of lipid transport	ISO	J:164563
Biological Process	GO:0048550	negative regulation of pinocytosis	ISO	J:164563
Biological Process	GO:0045861	negative regulation of proteolysis	IMP	J:142844
Biological Process	GO:1903573	negative regulation of response to endoplasmic reticulum stress	IDA	J:206173
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:160160
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0036151	phosphatidylcholine acyl-chain remodeling	IMP	J:206173
Biological Process	GO:0010875	positive regulation of cholesterol efflux	ISO	J:164563
Biological Process	GO:0010875	positive regulation of cholesterol efflux	IDA	J:135705
Biological Process	GO:0010875	positive regulation of cholesterol efflux	IDA	J:123957
Biological Process	GO:0010875	positive regulation of cholesterol efflux	IGI	J:200990
Biological Process	GO:0032376	positive regulation of cholesterol transport	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045723	positive regulation of fatty acid biosynthetic process	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:0090108	positive regulation of high-density lipoprotein particle assembly	IDA	J:135705
Biological Process	GO:0090108	positive regulation of high-density lipoprotein particle assembly	IDA	J:123957
Biological Process	GO:0010884	positive regulation of lipid storage	IMP	J:142844
Biological Process	GO:0051006	positive regulation of lipoprotein lipase activity	ISO	J:164563
Biological Process	GO:1902895	positive regulation of miRNA transcription	IDA	J:314370
Biological Process	GO:0090187	positive regulation of pancreatic juice secretion	IMP	J:142844
Biological Process	GO:0051247	positive regulation of protein metabolic process	ISO	J:164563
Biological Process	GO:0090340	positive regulation of secretion of lysosomal enzymes	IMP	J:142844
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:135705
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:154834
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0010867	positive regulation of triglyceride biosynthetic process	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:89079
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IGI	J:23077
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	ISO	J:155856

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23