Abca7 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Abca7
ATP-binding cassette, sub-family A member 7
MGI:1351646

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0140359	ABC-type transporter activity	IEA	J:72247
Molecular Function	GO:0034188	apolipoprotein A-I receptor activity	ISO	J:164563
Molecular Function	GO:0034188	apolipoprotein A-I receptor activity	IDA	J:207821
Molecular Function	GO:0034188	apolipoprotein A-I receptor activity	IBA	J:265628
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0140328	floppase activity	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0090554	phosphatidylcholine floppase activity	ISO	J:164563
Molecular Function	GO:0090554	phosphatidylcholine floppase activity	IBA	J:265628
Molecular Function	GO:0090556	phosphatidylserine floppase activity	ISO	J:164563
Molecular Function	GO:0090556	phosphatidylserine floppase activity	IBA	J:265628
Molecular Function	GO:0005548	phospholipid transporter activity	ISO	J:164563
Molecular Function	GO:0005548	phospholipid transporter activity	IDA	J:94706
Molecular Function	GO:0005515	protein binding	IPI	J:207821
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:94706
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	IDA	J:206915
Cellular Component	GO:0009986	cell surface	IDA	J:207821
Cellular Component	GO:0005737	cytoplasm	IDA	J:268026
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0097386	glial cell projection	IDA	J:268026
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005622	intracellular anatomical structure	IDA	J:94706
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IBA	J:265628
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0001891	phagocytic cup	IDA	J:112621
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0032587	ruffle membrane	IDA	J:112621
Biological Process	GO:0150094	amyloid-beta clearance by cellular catabolic process	IMP	J:268026
Biological Process	GO:0034205	amyloid-beta formation	ISO	J:164563
Biological Process	GO:0034205	amyloid-beta formation	IMP	J:225870
Biological Process	GO:0038027	apolipoprotein A-I-mediated signaling pathway	IMP	J:206915
Biological Process	GO:0038027	apolipoprotein A-I-mediated signaling pathway	IDA	J:207821
Biological Process	GO:0038027	apolipoprotein A-I-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0033344	cholesterol efflux	IMP	J:268026
Biological Process	GO:0033344	cholesterol efflux	ISO	J:164563
Biological Process	GO:0033344	cholesterol efflux	IBA	J:265628
Biological Process	GO:0034380	high-density lipoprotein particle assembly	ISO	J:164563
Biological Process	GO:0006869	lipid transport	IEA	J:60000
Biological Process	GO:0007613	memory	IMP	J:196282
Biological Process	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process	IDA	J:206916
Biological Process	GO:1902430	negative regulation of amyloid-beta formation	IDA	J:206916
Biological Process	GO:1902430	negative regulation of amyloid-beta formation	IMP	J:196282
Biological Process	GO:1902430	negative regulation of amyloid-beta formation	IMP	J:231748
Biological Process	GO:0045806	negative regulation of endocytosis	IMP	J:225870
Biological Process	GO:0043409	negative regulation of MAPK cascade	IMP	J:231748
Biological Process	GO:1903898	negative regulation of PERK-mediated unfolded protein response	IMP	J:231748
Biological Process	GO:0018149	peptide cross-linking	IDA	J:207821
Biological Process	GO:0006909	phagocytosis	IEA	J:60000
Biological Process	GO:0033700	phospholipid efflux	ISO	J:164563
Biological Process	GO:0033700	phospholipid efflux	IMP	J:268026
Biological Process	GO:0033700	phospholipid efflux	IBA	J:265628
Biological Process	GO:0033700	phospholipid efflux	IDA	J:94706
Biological Process	GO:0045332	phospholipid translocation	ISO	J:164563
Biological Process	GO:0044857	plasma membrane raft organization	IMP	J:269558
Biological Process	GO:1900223	positive regulation of amyloid-beta clearance	IMP	J:196282
Biological Process	GO:0010875	positive regulation of cholesterol efflux	IDA	J:206916
Biological Process	GO:1901076	positive regulation of engulfment of apoptotic cell	IMP	J:112621
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IMP	J:112621
Biological Process	GO:0050766	positive regulation of phagocytosis	IMP	J:268026
Biological Process	GO:0050766	positive regulation of phagocytosis	IMP	J:206915
Biological Process	GO:1902995	positive regulation of phospholipid efflux	IDA	J:207821
Biological Process	GO:2000010	positive regulation of protein localization to cell surface	IMP	J:269558
Biological Process	GO:0034504	protein localization to nucleus	IDA	J:206916
Biological Process	GO:1902991	regulation of amyloid precursor protein catabolic process	ISO	J:164563
Biological Process	GO:0019216	regulation of lipid metabolic process	IMP	J:231748
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0008542	visual learning	IMP	J:231748

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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