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GO Annotations Graph
Symbol
Name
ID
Map3k12
mitogen-activated protein kinase kinase kinase 12
MGI:1346881

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0004706JUN kinase kinase kinase activityIBAJ:265628
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0004709MAP kinase kinase kinase activityIEAJ:72245
Molecular FunctionGO:0004709MAP kinase kinase kinase activityIEAJ:72247
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0042803protein homodimerization activityIDAJ:113678
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0019901protein kinase bindingISOJ:164563
Molecular FunctionGO:0043539protein serine/threonine kinase activator activityIMPJ:236918
Molecular FunctionGO:0004674protein serine/threonine kinase activityIMPJ:236918
Molecular FunctionGO:0004674protein serine/threonine kinase activityIDAJ:113678
Molecular FunctionGO:0004674protein serine/threonine kinase activityIDAJ:20630
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Cellular ComponentGO:0030424axonIDAJ:132726
Cellular ComponentGO:0005737cytoplasmIEAJ:60000
Cellular ComponentGO:0005829cytosolIDAJ:113678
Cellular ComponentGO:0030426growth coneIDAJ:132726
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005886plasma membraneIDAJ:113678
Biological ProcessGO:0007254JNK cascadeIMPJ:236918
Biological ProcessGO:2000672negative regulation of motor neuron apoptotic processIMPJ:215576
Biological ProcessGO:0018105peptidyl-serine phosphorylationIMPJ:236918
Biological ProcessGO:0018105peptidyl-serine phosphorylationIDAJ:20630
Biological ProcessGO:0018107peptidyl-threonine phosphorylationIDAJ:20630
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionISOJ:164563
Biological ProcessGO:0070374positive regulation of ERK1 and ERK2 cascadeISOJ:164563
Biological ProcessGO:0043507positive regulation of JUN kinase activityIMPJ:236918
Biological ProcessGO:0045860positive regulation of protein kinase activityIMPJ:236918
Biological ProcessGO:0043687post-translational protein modificationIDAJ:113678
Biological ProcessGO:0046777protein autophosphorylationIDAJ:113678
Biological ProcessGO:0046777protein autophosphorylationIDAJ:20630
Biological ProcessGO:0006468protein phosphorylationISOJ:164563

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory