GO Annotations Graph

• Symbol: Hax1
• Name: HCLS1 associated X-1
• ID: MGI:1346319

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019966	interleukin-1 binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:333168
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0005515	protein binding	IPI	J:132627
Molecular Function	GO:0005515	protein binding	IPI	J:175122
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Cellular Component	GO:0015629	actin cytoskeleton	IDA	J:175122
Cellular Component	GO:0015629	actin cytoskeleton	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	IBA	J:265628
Cellular Component	GO:0030136	clathrin-coated vesicle	ISO	J:155856
Cellular Component	GO:0030136	clathrin-coated vesicle	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:175122
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:175122
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0030027	lamellipodium	IDA	J:175122
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005758	mitochondrial intermembrane space	ISO	J:164563
Cellular Component	GO:0005759	mitochondrial matrix	IDA	J:333168
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	IDA	J:57557
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0016529	sarcoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0016529	sarcoplasmic reticulum	IDA	J:155565
Cellular Component	GO:0016529	sarcoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:164563
Biological Process	GO:0007166	cell surface receptor signaling pathway	TAS	J:57557
Biological Process	GO:0071345	cellular response to cytokine stimulus	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	IBA	J:265628
Biological Process	GO:2000251	positive regulation of actin cytoskeleton reorganization	ISO	J:164563
Biological Process	GO:0030854	positive regulation of granulocyte differentiation	ISO	J:164563
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	ISO	J:164563
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0030833	regulation of actin filament polymerization	ISO	J:164563
Biological Process	GO:0030833	regulation of actin filament polymerization	IBA	J:265628