GO Annotations Graph

• Symbol: Pacsin1
• Name: protein kinase C and casein kinase substrate in neurons 1
• ID: MGI:1345181

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008092	cytoskeletal protein binding	IDA	J:66805
Molecular Function	GO:0042802	identical protein binding	IPI	J:160320
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0005543	phospholipid binding	ISO	J:164563
Molecular Function	GO:0005543	phospholipid binding	ISO	J:155856
Molecular Function	GO:0005543	phospholipid binding	IDA	J:160320
Molecular Function	GO:0005543	phospholipid binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:201934
Molecular Function	GO:0005515	protein binding	IPI	J:201934
Molecular Function	GO:0005515	protein binding	IPI	J:66805
Molecular Function	GO:0005515	protein binding	IPI	J:66805
Molecular Function	GO:0005515	protein binding	IPI	J:66805
Molecular Function	GO:0005515	protein binding	IPI	J:66805
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0030137	COPI-coated vesicle	IDA	J:55204
Cellular Component	GO:0005737	cytoplasm	IDA	J:160320
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:66805
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005768	endosome	IBA	J:265628
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0043005	neuron projection	IEA	J:60000
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0098684	photoreceptor ribbon synapse	IDA	J:199646
Cellular Component	GO:0098684	photoreceptor ribbon synapse	IDA	J:199646
Cellular Component	GO:0098684	photoreceptor ribbon synapse	IDA	J:199646
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0098839	postsynaptic density membrane	ISO	J:155856
Cellular Component	GO:0098793	presynapse	IDA	J:180017
Cellular Component	GO:0098833	presynaptic endocytic zone	IDA	J:199646
Cellular Component	GO:0098833	presynaptic endocytic zone	IDA	J:199646
Cellular Component	GO:0098833	presynaptic endocytic zone	IDA	J:199646
Cellular Component	GO:0032587	ruffle membrane	IDA	J:160320
Cellular Component	GO:0045202	synapse	IDA	J:180017
Cellular Component	GO:0045202	synapse	ISO	J:155856
Biological Process	GO:0007015	actin filament organization	IEA	J:72247
Biological Process	GO:0007010	cytoskeleton organization	ISO	J:155856
Biological Process	GO:0007010	cytoskeleton organization	IBA	J:265628
Biological Process	GO:0006897	endocytosis	IEA	J:60000
Biological Process	GO:0045806	negative regulation of endocytosis	IDA	J:66805
Biological Process	GO:0048666	neuron development	IEA	J:72247
Biological Process	GO:0048812	neuron projection morphogenesis	ISO	J:155856
Biological Process	GO:0048812	neuron projection morphogenesis	IBA	J:265628
Biological Process	GO:0097320	plasma membrane tubulation	ISO	J:164563
Biological Process	GO:0097320	plasma membrane tubulation	IMP	J:160320
Biological Process	GO:0097320	plasma membrane tubulation	ISO	J:155856
Biological Process	GO:0097320	plasma membrane tubulation	IBA	J:265628
Biological Process	GO:1900006	positive regulation of dendrite development	ISO	J:155856
Biological Process	GO:1900006	positive regulation of dendrite development	IBA	J:265628
Biological Process	GO:0072657	protein localization to membrane	IMP	J:180017
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:155856
Biological Process	GO:0030100	regulation of endocytosis	IBA	J:265628
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	ISO	J:155856
Biological Process	GO:0007165	signal transduction	TAS	J:55204
Biological Process	GO:0048488	synaptic vesicle endocytosis	IDA	J:180017
Biological Process	GO:0048488	synaptic vesicle endocytosis	IDA	J:180017
Biological Process	GO:0048488	synaptic vesicle endocytosis	IDA	J:180017
Biological Process	GO:0048488	synaptic vesicle endocytosis	IMP	J:180017
Biological Process	GO:0048488	synaptic vesicle endocytosis	IDA	J:180017