GO Annotations Graph

• Symbol: Aicda
• Name: activation-induced cytidine deaminase
• ID: MGI:1342279

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0004126	cytidine deaminase activity	IMP	J:82919
Molecular Function	GO:0004126	cytidine deaminase activity	ISO	J:164563
Molecular Function	GO:0004126	cytidine deaminase activity	IBA	J:265628
Molecular Function	GO:0004126	cytidine deaminase activity	IDA	J:55852
Molecular Function	GO:0047844	deoxycytidine deaminase activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:72247
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:170571
Molecular Function	GO:0005515	protein binding	IPI	J:199999
Molecular Function	GO:0005515	protein binding	IPI	J:172192
Molecular Function	GO:0003723	RNA binding	IBA	J:265628
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IC	J:126758
Cellular Component	GO:0000932	P-body	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IMP	J:141184
Biological Process	GO:0009972	cytidine deamination	IMP	J:82919
Biological Process	GO:0016554	cytidine to uridine editing	IBA	J:265628
Biological Process	GO:0042742	defense response to bacterium	IMP	J:88357
Biological Process	GO:0042742	defense response to bacterium	IGI	J:88357
Biological Process	GO:0051607	defense response to virus	IBA	J:265628
Biological Process	GO:0070383	DNA cytosine deamination	IBA	J:265628
Biological Process	GO:0080111	DNA demethylation	ISO	J:164563
Biological Process	GO:0080111	DNA demethylation	IBA	J:265628
Biological Process	GO:0045190	isotype switching	IMP	J:172192
Biological Process	GO:0045190	isotype switching	IMP	J:126758
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:0090310	negative regulation of DNA methylation-dependent heterochromatin formation	ISO	J:164563
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	IBA	J:265628
Biological Process	GO:0010529	negative regulation of transposition	IBA	J:265628
Biological Process	GO:0033262	regulation of nuclear cell cycle DNA replication	ISO	J:164563
Biological Process	GO:0016445	somatic diversification of immunoglobulins	ISO	J:164563
Biological Process	GO:0016446	somatic hypermutation of immunoglobulin genes	ISO	J:164563