GO Annotations Graph

• Symbol: Pla2g2d
• Name: phospholipase A2, group IID
• ID: MGI:1341796

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	IDA	J:58155
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	IDA	J:201008
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	ISO	J:164563
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	IBA	J:265628
Molecular Function	GO:0043395	heparan sulfate proteoglycan binding	IDA	J:150812
Molecular Function	GO:0008201	heparin binding	IDA	J:150812
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004623	phospholipase A2 activity	IEA	J:72247
Molecular Function	GO:0004623	phospholipase A2 activity	IEA	J:72245
Molecular Function	GO:0005543	phospholipid binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IDA	J:58155
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0050482	arachidonic acid secretion	IEA	J:72247
Biological Process	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	IDA	J:150812
Biological Process	GO:0006954	inflammatory response	IEA	J:60000
Biological Process	GO:0016042	lipid catabolic process	IEA	J:72247
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0050868	negative regulation of T cell activation	IDA	J:150812
Biological Process	GO:0042130	negative regulation of T cell proliferation	IBA	J:265628
Biological Process	GO:0042130	negative regulation of T cell proliferation	IDA	J:150812
Biological Process	GO:0046470	phosphatidylcholine metabolic process	IDA	J:58155
Biological Process	GO:0046470	phosphatidylcholine metabolic process	ISO	J:164563
Biological Process	GO:0046337	phosphatidylethanolamine metabolic process	IDA	J:201008
Biological Process	GO:0046471	phosphatidylglycerol metabolic process	IDA	J:58155
Biological Process	GO:0006644	phospholipid metabolic process	IBA	J:265628
Biological Process	GO:0002864	regulation of acute inflammatory response to antigenic stimulus	IMP	J:201008