GO Annotations Graph

• Symbol: Stc2
• Name: stanniocalcin 2
• ID: MGI:1316731

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0020037	heme binding	ISO	J:164563
Molecular Function	GO:0005179	hormone activity	IEA	J:60000
Molecular Function	GO:0005179	hormone activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:175075
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:94132
Cellular Component	GO:0005576	extracellular region	ISO	J:73065
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:94132
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Biological Process	GO:0055074	calcium ion homeostasis	IGI	J:183281
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	IMP	J:94132
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IBA	J:265628
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IMP	J:175075
Biological Process	GO:0006874	intracellular calcium ion homeostasis	ISO	J:73065
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0040015	negative regulation of multicellular organism growth	IMP	J:136007
Biological Process	GO:0046885	regulation of hormone biosynthetic process	ISO	J:164563
Biological Process	GO:2000118	regulation of sodium-dependent phosphate transport	ISO	J:73065
Biological Process	GO:2001256	regulation of store-operated calcium entry	IMP	J:175075
Biological Process	GO:0034976	response to endoplasmic reticulum stress	IMP	J:175075
Biological Process	GO:0006979	response to oxidative stress	IMP	J:175075