GO Annotations Graph

• Symbol: Fhit
• Name: fragile histidine triad gene
• ID: MGI:1277947

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0043530	adenosine 5'-monophosphoramidase activity	ISO	J:164563
Molecular Function	GO:0047627	adenylylsulfatase activity	ISO	J:164563
Molecular Function	GO:0047352	adenylylsulfate-ammonia adenylyltransferase activity	ISO	J:164563
Molecular Function	GO:0047710	bis(5'-adenosyl)-triphosphatase activity	ISO	J:164563
Molecular Function	GO:0047710	bis(5'-adenosyl)-triphosphatase activity	ISO	J:155856
Molecular Function	GO:0047710	bis(5'-adenosyl)-triphosphatase activity	ISS	J:58686
Molecular Function	GO:0047710	bis(5'-adenosyl)-triphosphatase activity	IBA	J:265628
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0016151	nickel cation binding	ISO	J:155856
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:48953
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0001650	fibrillar center	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0015964	diadenosine triphosphate catabolic process	ISO	J:155856
Biological Process	GO:0015964	diadenosine triphosphate catabolic process	ISS	J:58686
Biological Process	GO:0015964	diadenosine triphosphate catabolic process	ISO	J:164563
Biological Process	GO:0015964	diadenosine triphosphate catabolic process	IBA	J:265628
Biological Process	GO:0006260	DNA replication	IDA	J:92253
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	ISO	J:164563
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	IBA	J:265628
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	IBA	J:265628
Biological Process	GO:0006163	purine nucleotide metabolic process	ISO	J:164563
Biological Process	GO:0006163	purine nucleotide metabolic process	IBA	J:265628