GO Annotations Graph

• Symbol: Dffa
• Name: DNA fragmentation factor, alpha subunit
• ID: MGI:1196227

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0060703	deoxyribonuclease inhibitor activity	ISO	J:164563
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:200478
Molecular Function	GO:0005515	protein binding	IPI	J:273504
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0044183	protein folding chaperone	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:96974
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0006309	apoptotic DNA fragmentation	IEA	J:72247
Biological Process	GO:0006915	apoptotic process	IEA	J:72247
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0061077	chaperone-mediated protein folding	ISO	J:164563
Biological Process	GO:1902511	negative regulation of apoptotic DNA fragmentation	ISO	J:164563
Biological Process	GO:1902511	negative regulation of apoptotic DNA fragmentation	ISO	J:96974
Biological Process	GO:1902511	negative regulation of apoptotic DNA fragmentation	IMP	J:88144
Biological Process	GO:1902511	negative regulation of apoptotic DNA fragmentation	IMP	J:77791
Biological Process	GO:0032076	negative regulation of deoxyribonuclease activity	ISO	J:164563
Biological Process	GO:1900118	negative regulation of execution phase of apoptosis	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	IMP	J:88144
Biological Process	GO:0042981	regulation of apoptotic process	IBA	J:265628
Biological Process	GO:0070242	thymocyte apoptotic process	IMP	J:77791