GO Annotations Graph

• Symbol: Inpp5k
• Name: inositol polyphosphate 5-phosphatase K
• ID: MGI:1194899

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0016312	inositol bisphosphate phosphatase activity	IMP	J:177248
Molecular Function	GO:0016312	inositol bisphosphate phosphatase activity	ISO	J:164563
Molecular Function	GO:0016312	inositol bisphosphate phosphatase activity	IBA	J:265628
Molecular Function	GO:0016312	inositol bisphosphate phosphatase activity	ISO	J:139745
Molecular Function	GO:0046030	inositol trisphosphate phosphatase activity	ISO	J:164563
Molecular Function	GO:0046030	inositol trisphosphate phosphatase activity	ISO	J:139745
Molecular Function	GO:0052659	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity	IEA	J:72245
Molecular Function	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity	IEA	J:72245
Molecular Function	GO:0004445	inositol-polyphosphate 5-phosphatase activity	IEA	J:72245
Molecular Function	GO:0016791	phosphatase activity	IEA	J:72247
Molecular Function	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	ISO	J:164563
Molecular Function	GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	ISO	J:164563
Molecular Function	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	ISO	J:164563
Molecular Function	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	IDA	J:178554
Molecular Function	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	IBA	J:265628
Molecular Function	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	ISO	J:164563
Molecular Function	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:188803
Molecular Function	GO:0005000	vasopressin receptor activity	IDA	J:178554
Cellular Component	GO:0005737	cytoplasm	IDA	J:178554
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:185086
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:188803
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:82579
Cellular Component	GO:0016020	membrane	ISO	J:82579
Cellular Component	GO:0043005	neuron projection	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0001726	ruffle	IBA	J:265628
Cellular Component	GO:0001726	ruffle	ISO	J:82579
Cellular Component	GO:0032587	ruffle membrane	ISO	J:164563
Cellular Component	GO:0005802	trans-Golgi network	ISO	J:164563
Biological Process	GO:0071320	cellular response to cAMP	IDA	J:178554
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	ISO	J:164563
Biological Process	GO:0032870	cellular response to hormone stimulus	IDA	J:178554
Biological Process	GO:0032869	cellular response to insulin stimulus	ISO	J:164563
Biological Process	GO:0071356	cellular response to tumor necrosis factor	ISO	J:164563
Biological Process	GO:0016311	dephosphorylation	ISO	J:164563
Biological Process	GO:0016311	dephosphorylation	IDA	J:178554
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IDA	J:178554
Biological Process	GO:0042593	glucose homeostasis	IMP	J:177248
Biological Process	GO:0042593	glucose homeostasis	IMP	J:139745
Biological Process	GO:0001701	in utero embryonic development	IMP	J:139745
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0043922	negative regulation by host of viral transcription	ISO	J:164563
Biological Process	GO:0051926	negative regulation of calcium ion transport	ISO	J:164563
Biological Process	GO:0035305	negative regulation of dephosphorylation	IMP	J:177248
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:178554
Biological Process	GO:0010829	negative regulation of glucose transmembrane transport	ISO	J:164563
Biological Process	GO:2000466	negative regulation of glycogen (starch) synthase activity	IMP	J:177248
Biological Process	GO:0045719	negative regulation of glycogen biosynthetic process	IMP	J:177248
Biological Process	GO:0045719	negative regulation of glycogen biosynthetic process	ISO	J:164563
Biological Process	GO:0045719	negative regulation of glycogen biosynthetic process	IBA	J:265628
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	IMP	J:177248
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	IBA	J:265628
Biological Process	GO:0043407	negative regulation of MAP kinase activity	ISO	J:164563
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	IMP	J:177248
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	IBA	J:265628
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	IMP	J:139745
Biological Process	GO:0010801	negative regulation of peptidyl-threonine phosphorylation	ISO	J:164563
Biological Process	GO:0006469	negative regulation of protein kinase activity	ISO	J:164563
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	IMP	J:177248
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	ISO	J:164563
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	IBA	J:265628
Biological Process	GO:0001933	negative regulation of protein phosphorylation	IDA	J:178554
Biological Process	GO:0090315	negative regulation of protein targeting to membrane	ISO	J:164563
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	ISO	J:164563
Biological Process	GO:0051497	negative regulation of stress fiber assembly	ISO	J:164563
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	ISO	J:164563
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	IBA	J:265628
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	ISO	J:82579
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:178554
Biological Process	GO:2001153	positive regulation of renal water transport	IDA	J:178554
Biological Process	GO:0035810	positive regulation of urine volume	IDA	J:178554
Biological Process	GO:0072659	protein localization to plasma membrane	IDA	J:178554
Biological Process	GO:0005979	regulation of glycogen biosynthetic process	IMP	J:177248
Biological Process	GO:0032868	response to insulin	IMP	J:139745
Biological Process	GO:0097178	ruffle assembly	ISO	J:164563