GO Annotations Graph

• Symbol: Nrp2
• Name: neuropilin 2
• ID: MGI:1100492

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008201	heparin binding	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:106852
Molecular Function	GO:0005515	protein binding	IPI	J:91658
Molecular Function	GO:0005515	protein binding	IPI	J:57968
Molecular Function	GO:0017154	semaphorin receptor activity	IBA	J:265628
Molecular Function	GO:0017154	semaphorin receptor activity	IDA	J:91658
Molecular Function	GO:0005021	vascular endothelial growth factor receptor activity	IEA	J:72247
Cellular Component	GO:0030424	axon	IBA	J:265628
Cellular Component	GO:0030424	axon	IDA	J:96969
Cellular Component	GO:0098978	glutamatergic synapse	IBA	J:265628
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:216166
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:216166
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:156473
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:156473
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:156473
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:156473
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-549062
Cellular Component	GO:0005886	plasma membrane	IC	J:91658
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:216166
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:216166
Biological Process	GO:0001525	angiogenesis	IEA	J:72247
Biological Process	GO:0048846	axon extension involved in axon guidance	IMP	J:187616
Biological Process	GO:0007411	axon guidance	IBA	J:265628
Biological Process	GO:0007411	axon guidance	IMP	J:98330
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:1904835	dorsal root ganglion morphogenesis	IMP	J:149474
Biological Process	GO:0021612	facial nerve structural organization	IMP	J:134486
Biological Process	GO:1903375	facioacoustic ganglion development	IMP	J:134486
Biological Process	GO:0021828	gonadotrophin-releasing hormone neuronal migration to the hypothalamus	IMP	J:166892
Biological Process	GO:0007507	heart development	IGI	J:93799
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0050919	negative chemotaxis	IGI	J:104892
Biological Process	GO:0050919	negative chemotaxis	IMP	J:98330
Biological Process	GO:0021675	nerve development	IMP	J:187616
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:1901166	neural crest cell migration involved in autonomic nervous system development	IMP	J:134486
Biological Process	GO:1901166	neural crest cell migration involved in autonomic nervous system development	IMP	J:149474
Biological Process	GO:0001764	neuron migration	IMP	J:166892
Biological Process	GO:0003148	outflow tract septum morphogenesis	IGI	J:225355
Biological Process	GO:0099175	regulation of postsynapse organization	IDA	J:156473
Biological Process	GO:0099175	regulation of postsynapse organization	IMP	J:156473
Biological Process	GO:0099175	regulation of postsynapse organization	IDA	J:156473
Biological Process	GO:0099175	regulation of postsynapse organization	IDA	J:156473
Biological Process	GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	IMP	J:187616
Biological Process	GO:0097374	sensory neuron axon guidance	IMP	J:134486
Biological Process	GO:0061549	sympathetic ganglion development	IMP	J:187616
Biological Process	GO:0097490	sympathetic neuron projection extension	IMP	J:187616
Biological Process	GO:0097491	sympathetic neuron projection guidance	IMP	J:187616
Biological Process	GO:0061551	trigeminal ganglion development	IMP	J:134486
Biological Process	GO:0036484	trunk neural crest cell migration	IMP	J:104892
Biological Process	GO:0038084	vascular endothelial growth factor signaling pathway	IEA	J:72247
Biological Process	GO:0036486	ventral trunk neural crest cell migration	IMP	J:149474
Biological Process	GO:0021649	vestibulocochlear nerve structural organization	IMP	J:134486