GO Annotations Graph

• Symbol: Cd81
• Name: CD81 antigen
• ID: MGI:1096398

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015485	cholesterol binding	ISO	J:164563
Molecular Function	GO:0005178	integrin binding	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0042289	MHC class II protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:271693
Molecular Function	GO:0005515	protein binding	IPI	J:227372
Molecular Function	GO:0005515	protein binding	IPI	J:72396
Molecular Function	GO:0005515	protein binding	IPI	J:72670
Molecular Function	GO:1990459	transferrin receptor binding	ISO	J:164563
Molecular Function	GO:0001618	virus receptor activity	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0009925	basal plasma membrane	ISO	J:164563
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0070062	extracellular exosome	ISO	J:164563
Cellular Component	GO:0001772	immunological synapse	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:227372
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0097197	tetraspanin-enriched microdomain	ISO	J:164563
Cellular Component	GO:0031982	vesicle	ISO	J:164563
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0035783	CD4-positive, alpha-beta T cell costimulation	ISO	J:164563
Biological Process	GO:0071404	cellular response to low-density lipoprotein particle stimulus	IDA	J:227372
Biological Process	GO:0002455	humoral immune response mediated by circulating immunoglobulin	ISO	J:164563
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0001771	immunological synapse formation	ISO	J:164563
Biological Process	GO:0034238	macrophage fusion	IMP	J:83795
Biological Process	GO:0034238	macrophage fusion	ISO	J:164563
Biological Process	GO:0014905	myoblast fusion involved in skeletal muscle regeneration	IMP	J:271693
Biological Process	GO:0072675	osteoclast fusion	IMP	J:83795
Biological Process	GO:0043128	positive regulation of 1-phosphatidylinositol 4-kinase activity	ISO	J:164563
Biological Process	GO:1905676	positive regulation of adaptive immune memory response	ISO	J:164563
Biological Process	GO:0050871	positive regulation of B cell activation	IMP	J:195115
Biological Process	GO:0030890	positive regulation of B cell proliferation	TAS	J:114144
Biological Process	GO:0030890	positive regulation of B cell proliferation	ISO	J:164563
Biological Process	GO:0050861	positive regulation of B cell receptor signaling pathway	IMP	J:195115
Biological Process	GO:0050861	positive regulation of B cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation	ISO	J:164563
Biological Process	GO:0030307	positive regulation of cell growth	TAS	J:114144
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0002863	positive regulation of inflammatory response to antigenic stimulus	IMP	J:65423
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:164563
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:1904352	positive regulation of protein catabolic process in the vacuole	ISO	J:164563
Biological Process	GO:0070863	positive regulation of protein exit from endoplasmic reticulum	ISO	J:164563
Biological Process	GO:1903911	positive regulation of receptor clustering	ISO	J:164563
Biological Process	GO:1903911	positive regulation of receptor clustering	IMP	J:195115
Biological Process	GO:2001190	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	IMP	J:65423
Biological Process	GO:2001190	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	ISO	J:164563
Biological Process	GO:0050862	positive regulation of T cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:2000553	positive regulation of T-helper 2 cell cytokine production	ISO	J:164563
Biological Process	GO:2000553	positive regulation of T-helper 2 cell cytokine production	IMP	J:65423
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0008104	protein localization	ISO	J:164563
Biological Process	GO:0061462	protein localization to lysosome	ISO	J:164563
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0031623	receptor internalization	IDA	J:227372
Biological Process	GO:2000145	regulation of cell motility	IGI	J:72670
Biological Process	GO:0042127	regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:1905521	regulation of macrophage migration	IDA	J:141975
Biological Process	GO:0031647	regulation of protein stability	ISO	J:164563