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GO Annotations Graph
Symbol
Name
ID
Cxcr4
chemokine (C-X-C motif) receptor 4
MGI:109563

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0003779actin bindingISOJ:164563
Molecular FunctionGO:0016494C-X-C chemokine receptor activityISOJ:155856
Molecular FunctionGO:0004950chemokine receptor activityIEAJ:72247
Molecular FunctionGO:0019955cytokine bindingIEAJ:72247
Molecular FunctionGO:0008144drug bindingISOJ:155856
Molecular FunctionGO:0004930G-protein coupled receptor activityIEAJ:72247
Molecular FunctionGO:0004930G-protein coupled receptor activityIEAJ:60000
Molecular FunctionGO:0032027myosin light chain bindingISOJ:164563
Molecular FunctionGO:0005515protein bindingIPIJ:135334
Molecular FunctionGO:0004871signal transducer activityIEAJ:60000
Molecular FunctionGO:0043130ubiquitin bindingISOJ:164563
Molecular FunctionGO:0031625ubiquitin protein ligase bindingISOJ:164563
Cellular ComponentGO:0030054cell junctionIEAJ:60000
Cellular ComponentGO:0031252cell leading edgeISOJ:164563
Cellular ComponentGO:0009986cell surfaceISOJ:164563
Cellular ComponentGO:0009986cell surfaceIDAJ:190263
Cellular ComponentGO:0009986cell surfaceISOJ:200103
Cellular ComponentGO:0005911cell-cell junctionIDAJ:205441
Cellular ComponentGO:0031410cytoplasmic vesicleISOJ:164563
Cellular ComponentGO:0016023cytoplasmic, membrane-bounded vesicleISOJ:164563
Cellular ComponentGO:0005769early endosomeISOJ:164563
Cellular ComponentGO:0005768endosomeISOJ:155856
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:141392
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0030426growth coneIDAJ:101029
Cellular ComponentGO:0016021integral component of membraneIEAJ:72247
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0005770late endosomeISOJ:164563
Cellular ComponentGO:0005764lysosomeISOJ:164563
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Biological ProcessGO:0001667ameboidal-type cell migrationIMPJ:98453
Biological ProcessGO:0035904aorta developmentIMPJ:222159
Biological ProcessGO:0007420brain developmentIMPJ:79852
Biological ProcessGO:0019722calcium-mediated signalingISOJ:147597
Biological ProcessGO:0060048cardiac muscle contractionISOJ:155856
Biological ProcessGO:0016477cell migrationISOJ:155856
Biological ProcessGO:0071345cellular response to cytokine stimulusISOJ:164563
Biological ProcessGO:0070098chemokine-mediated signaling pathwayISOJ:155856
Biological ProcessGO:0006935chemotaxisIEAJ:72247
Biological ProcessGO:0002064epithelial cell developmentISOJ:155856
Biological ProcessGO:0007186G-protein coupled receptor signaling pathwayISOJ:164563
Biological ProcessGO:0007281germ cell developmentIMPJ:84597
Biological ProcessGO:0008354germ cell migrationIMPJ:84597
Biological ProcessGO:0035701hematopoietic stem cell migrationIMPJ:178186
Biological ProcessGO:0008045motor neuron axon guidanceIMPJ:132726
Biological ProcessGO:0008045motor neuron axon guidanceIMPJ:101029
Biological ProcessGO:0043217myelin maintenanceIMPJ:161391
Biological ProcessGO:0007399nervous system developmentTASJ:69255
Biological ProcessGO:0001764neuron migrationIDAJ:84597
Biological ProcessGO:0001764neuron migrationISOJ:155856
Biological ProcessGO:0042119neutrophil activationIEAJ:72247
Biological ProcessGO:0009887organ morphogenesisTASJ:69256
Biological ProcessGO:0001569patterning of blood vesselsIMPJ:98453
Biological ProcessGO:0048714positive regulation of oligodendrocyte differentiationIMPJ:161391
Biological ProcessGO:0001934positive regulation of protein phosphorylationIMPJ:178186
Biological ProcessGO:0051924regulation of calcium ion transportISOJ:155856
Biological ProcessGO:0030334regulation of cell migrationIMPJ:84597
Biological ProcessGO:0030334regulation of cell migrationIGIJ:100909
Biological ProcessGO:0030334regulation of cell migrationIMPJ:79852
Biological ProcessGO:0050920regulation of chemotaxisISOJ:164563
Biological ProcessGO:0050920regulation of chemotaxisISOJ:155856
Biological ProcessGO:0043067regulation of programmed cell deathISOJ:155856
Biological ProcessGO:0007165signal transductionIEAJ:60000
Biological ProcessGO:0042098T cell proliferationIMPJ:82996
Biological ProcessGO:0022029telencephalon cell migrationISOJ:155856
Biological ProcessGO:0003281ventricular septum developmentIMPJ:222159


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/24/2023
MGI 6.22
The Jackson Laboratory