GO Annotations Graph

• Symbol: Jag1
• Name: jagged 1
• ID: MGI:1095416

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	NAS	J:58381
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0005112	Notch binding	IPI	J:88030
Molecular Function	GO:0005112	Notch binding	IPI	J:58381
Molecular Function	GO:0005112	Notch binding	ISO	J:164563
Molecular Function	GO:0005112	Notch binding	ISO	J:155856
Molecular Function	GO:0005112	Notch binding	IBA	J:265628
Molecular Function	GO:0005543	phospholipid binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:225411
Molecular Function	GO:0005515	protein binding	IPI	J:101173
Molecular Function	GO:0005515	protein binding	IPI	J:97329
Molecular Function	GO:0048018	receptor ligand activity	ISO	J:155856
Cellular Component	GO:0005912	adherens junction	IDA	J:208850
Cellular Component	GO:0045177	apical part of cell	IDA	J:97734
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:208850
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-2032378
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-2053963
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9012893
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9604251
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9604278
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-209162
Cellular Component	GO:0005886	plasma membrane	IDA	J:107414
Cellular Component	GO:0005886	plasma membrane	IDA	J:107414
Cellular Component	GO:0005886	plasma membrane	IDA	J:101173
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:67728
Biological Process	GO:0035909	aorta morphogenesis	IMP	J:152574
Biological Process	GO:0001974	blood vessel remodeling	IMP	J:54907
Biological Process	GO:0001974	blood vessel remodeling	IMP	J:54907
Biological Process	GO:0043010	camera-type eye development	IMP	J:54907
Biological Process	GO:0061309	cardiac neural crest cell development involved in outflow tract morphogenesis	IMP	J:152574
Biological Process	GO:0003215	cardiac right ventricle morphogenesis	IMP	J:152574
Biological Process	GO:0060411	cardiac septum morphogenesis	IMP	J:152574
Biological Process	GO:0007154	cell communication	IEA	J:72247
Biological Process	GO:0061073	ciliary body morphogenesis	IMP	J:197419
Biological Process	GO:0072017	distal tubule development	IEP	J:97734
Biological Process	GO:0061444	endocardial cushion cell development	IMP	J:152574
Biological Process	GO:0002085	inhibition of neuroepithelial cell differentiation	IMP	J:96080
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	ISO	J:155856
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IMP	J:107414
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IMP	J:107414
Biological Process	GO:0048839	inner ear development	IMP	J:149467
Biological Process	GO:0072070	loop of Henle development	IEP	J:97734
Biological Process	GO:0002011	morphogenesis of an epithelial sheet	IMP	J:74574
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:72247
Biological Process	GO:0045596	negative regulation of cell differentiation	ISO	J:155856
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:164563
Biological Process	GO:0022408	negative regulation of cell-cell adhesion	ISO	J:164563
Biological Process	GO:0001953	negative regulation of cell-matrix adhesion	ISO	J:164563
Biological Process	GO:0045602	negative regulation of endothelial cell differentiation	IDA	J:224042
Biological Process	GO:0045599	negative regulation of fat cell differentiation	IDA	J:89916
Biological Process	GO:0045665	negative regulation of neuron differentiation	IMP	J:156172
Biological Process	GO:0045665	negative regulation of neuron differentiation	IMP	J:96080
Biological Process	GO:2000737	negative regulation of stem cell differentiation	ISO	J:164563
Biological Process	GO:0072006	nephron development	IMP	J:198632
Biological Process	GO:0061101	neuroendocrine cell differentiation	IMP	J:96080
Biological Process	GO:0030182	neuron differentiation	IMP	J:156172
Biological Process	GO:0061314	Notch signaling involved in heart development	IMP	J:152574
Biological Process	GO:0061314	Notch signaling involved in heart development	ISO	J:164563
Biological Process	GO:0007219	Notch signaling pathway	TAS	J:97734
Biological Process	GO:0007219	Notch signaling pathway	ISO	J:155856
Biological Process	GO:0007219	Notch signaling pathway	ISO	J:164563
Biological Process	GO:0007219	Notch signaling pathway	IDA	J:212472
Biological Process	GO:0007219	Notch signaling pathway	IDA	J:218171
Biological Process	GO:0007219	Notch signaling pathway	IDA	J:97945
Biological Process	GO:0007219	Notch signaling pathway	IDA	J:97329
Biological Process	GO:0007219	Notch signaling pathway	IGI	J:217593
Biological Process	GO:0072015	podocyte development	IMP	J:198632
Biological Process	GO:0062043	positive regulation of cardiac epithelial to mesenchymal transition	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:0045639	positive regulation of myeloid cell differentiation	IDA	J:97945
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	IDA	J:88030
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	IDA	J:202853
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:152574
Biological Process	GO:0061156	pulmonary artery morphogenesis	ISO	J:164563
Biological Process	GO:0003184	pulmonary valve morphogenesis	ISO	J:164563
Biological Process	GO:0042127	regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0050678	regulation of epithelial cell proliferation	IGI	J:217593
Biological Process	GO:2000241	regulation of reproductive process	IGI	J:217593
Biological Process	GO:0032495	response to muramyl dipeptide	IDA	J:170396
Biological Process	GO:0002456	T cell mediated immunity	ISO	J:164563