GO Annotations Graph

• Symbol: Trpc4
• Name: transient receptor potential cation channel, subfamily C, member 4
• ID: MGI:109525

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:164563
Molecular Function	GO:0045296	cadherin binding	ISO	J:164563
Molecular Function	GO:0005262	calcium channel activity	ISO	J:155856
Molecular Function	GO:0070679	inositol 1,4,5 trisphosphate binding	IDA	J:95212
Molecular Function	GO:0070679	inositol 1,4,5 trisphosphate binding	IBA	J:265628
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:292529
Molecular Function	GO:0005515	protein binding	IPI	J:142574
Molecular Function	GO:0005515	protein binding	IPI	J:122666
Molecular Function	GO:0005515	protein binding	IPI	J:122666
Molecular Function	GO:0005515	protein binding	IPI	J:122666
Molecular Function	GO:0015279	store-operated calcium channel activity	ISO	J:164563
Molecular Function	GO:0015279	store-operated calcium channel activity	IBA	J:265628
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0034704	calcium channel complex	ISO	J:164563
Cellular Component	GO:0034703	cation channel complex	IBA	J:265628
Cellular Component	GO:0005901	caveola	IDA	J:76857
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0030863	cortical cytoskeleton	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0045121	membrane raft	IDA	J:122666
Cellular Component	GO:0005886	plasma membrane	IDA	J:95212
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:65272
Cellular Component	GO:0032991	protein-containing complex	IPI	J:122666
Cellular Component	GO:0032991	protein-containing complex	IPI	J:122666
Cellular Component	GO:0032991	protein-containing complex	IPI	J:122666
Biological Process	GO:0070509	calcium ion import	ISO	J:164563
Biological Process	GO:0070588	calcium ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006816	calcium ion transport	ISO	J:155856
Biological Process	GO:0014051	gamma-aminobutyric acid secretion	IMP	J:88211
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0048709	oligodendrocyte differentiation	IMP	J:145866
Biological Process	GO:0106129	positive regulation of store-operated calcium entry	ISO	J:155856
Biological Process	GO:0099605	regulation of action potential firing rate	ISO	J:155856
Biological Process	GO:0051924	regulation of calcium ion transport	ISO	J:155856
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	IBA	J:265628
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247